Resumé
OBJECTIVE To define the prevalence and pregnancy outcomes related to elevated fasting venous plasma glucose (FVPG) in a Danish pregnancy cohort. RESEARCH DESIGN AND METHODS This was an observational cohort study including 1,516 women without gestational diabetes mellitus (GDM) by Danish criteria. FVPG measured at 28 weeks’ gestation was related to pregnancy outcomes. RESULTS With use of the World Health Organization (WHO) 2013 threshold of FVPG ‡5.1 mmol/L, 40.1% of the cohort qualified as having GDM. There was no evidence of excess fetal growth, hypertension in pregnancy, or cesarean delivery in women with FVPG <5.6 mmol/L. CONCLUSIONS The WHO 2013 FVPG threshold for GDM is unsuitable for Denmark. It inappropriately labels as having GDM an unmanageably large number of women who are at low absolute risk of pregnancy complications.
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | Diabetes Care |
| Vol/bind | 41 |
| Udgave nummer | 7 |
| Sider (fra-til) | 1339-1342 |
| ISSN | 0149-5992 |
| DOI | |
| Status | Udgivet - jul. 2018 |
Fingeraftryk
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Gestational Diabetes Mellitus : Does One Size Fit All? A Challenge to Uniform Worldwide Diagnostic Thresholds. / McIntyre, H. David; Jensen, Dorte M; Jensen, Richard C.; Kyhl, Henriette B; Jensen, Tina K.; Glintborg, Dorte; Andersen, Marianne.
I: Diabetes Care, Bind 41, Nr. 7, 07.2018, s. 1339-1342.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
TY - JOUR
T1 - Gestational Diabetes Mellitus
T2 - Does One Size Fit All? A Challenge to Uniform Worldwide Diagnostic Thresholds
AU - McIntyre, H. David
AU - Jensen, Dorte M
AU - Jensen, Richard C.
AU - Kyhl, Henriette B
AU - Jensen, Tina K.
AU - Glintborg, Dorte
AU - Andersen, Marianne
N1 - © 2018 by the American Diabetes Association.
PY - 2018/7
Y1 - 2018/7
N2 - OBJECTIVE To define the prevalence and pregnancy outcomes related to elevated fasting venous plasma glucose (FVPG) in a Danish pregnancy cohort. RESEARCH DESIGN AND METHODS This was an observational cohort study including 1,516 women without gestational diabetes mellitus (GDM) by Danish criteria. FVPG measured at 28 weeks’ gestation was related to pregnancy outcomes. RESULTS With use of the World Health Organization (WHO) 2013 threshold of FVPG ‡5.1 mmol/L, 40.1% of the cohort qualified as having GDM. There was no evidence of excess fetal growth, hypertension in pregnancy, or cesarean delivery in women with FVPG <5.6 mmol/L. CONCLUSIONS The WHO 2013 FVPG threshold for GDM is unsuitable for Denmark. It inappropriately labels as having GDM an unmanageably large number of women who are at low absolute risk of pregnancy complications.
AB - OBJECTIVE To define the prevalence and pregnancy outcomes related to elevated fasting venous plasma glucose (FVPG) in a Danish pregnancy cohort. RESEARCH DESIGN AND METHODS This was an observational cohort study including 1,516 women without gestational diabetes mellitus (GDM) by Danish criteria. FVPG measured at 28 weeks’ gestation was related to pregnancy outcomes. RESULTS With use of the World Health Organization (WHO) 2013 threshold of FVPG ‡5.1 mmol/L, 40.1% of the cohort qualified as having GDM. There was no evidence of excess fetal growth, hypertension in pregnancy, or cesarean delivery in women with FVPG <5.6 mmol/L. CONCLUSIONS The WHO 2013 FVPG threshold for GDM is unsuitable for Denmark. It inappropriately labels as having GDM an unmanageably large number of women who are at low absolute risk of pregnancy complications.
KW - Adult
KW - Birth Weight
KW - Blood Glucose/analysis
KW - Cesarean Section/statistics & numerical data
KW - Cohort Studies
KW - Denmark/epidemiology
KW - Diabetes, Gestational/blood
KW - Fasting/blood
KW - Female
KW - Glucose Tolerance Test/standards
KW - Humans
KW - Infant, Newborn
KW - Infant, Newborn, Diseases/epidemiology
KW - Pregnancy
KW - Pregnancy Complications/epidemiology
KW - Pregnancy Outcome/epidemiology
KW - Prevalence
KW - Reference Values
U2 - 10.2337/dc17-2393
DO - 10.2337/dc17-2393
M3 - Journal article
VL - 41
SP - 1339
EP - 1342
JO - Diabetes Care
JF - Diabetes Care
SN - 0149-5992
IS - 7
ER -