Genetic KCa3.1-deficiency produces locomotor hyperactivity and alterations in cerebral monoamine levels
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
The calmodulin/calcium-activated K(+) channel KCa3.1 is expressed in red and white blood cells, epithelia and endothelia, and possibly central and peripheral neurons. However, our knowledge about its contribution to neurological functions and behavior is incomplete. Here, we investigated whether genetic deficiency or pharmacological activation of KCa3.1 change behavior and cerebral monoamine levels in mice.