Fragrance mix II in the baseline series contributes significantly to detection of fragrance allergy

Maria S Vølund Heisterberg, Klaus Ejner Andersen, Christian Avnstorp, Berit Kristensen, Axel Ove Kristensen, Knud Kaaber, Grete Laurberg, Torkil Menné, Niels Henrik Nielsen, Mette Sommerlund, Jens Thormann, Niels Veien, Susanne Vissing, Jeanne Duus Johansen

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Background: Fragrance mix II (FM II) is a relatively new screening marker for fragrance contact allergy. It was introduced in the patch test baseline series in Denmark in 2005 and contains six different fragrance chemicals commonly present in cosmetic products and which are known allergens. Aim: To investigate the diagnostic contribution of including FM II in the baseline series by comparing it with other screening markers of fragrance allergy: fragrance mix I (FM I), Myroxylon pereirae and hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC). Method: Retrospective study of 12 302 patients consecutively patch tested with FM II by members of the Danish Contact Dermatitis Group 2005-2008. Results: FM II gave a positive patch test in 553 patients (4.5%), and in 72.2% of these patients the reaction was judged to be clinically relevant. FM II ranked second in detecting fragrance allergy, after FM I. If FM II had not been included as a screening marker in the baseline series, 15.6% (n = 202) of individuals with fragrance allergy would not have been identified by the other fragrance screening markers (FM I, M. pereirae or HICC). Conclusion: FM II contributes substantially to detecting fragrance allergy. It ranked second among the fragrance screening markers tested in the baseline series and detects individuals with an allergy who otherwise would not have been identified.
OriginalsprogEngelsk
TidsskriftContact Dermatitis
Vol/bind63
Udgave nummer5
Sider (fra-til)270-276
Antal sider7
ISSN0105-1873
DOI
StatusUdgivet - 1. nov. 2010

Fingeraftryk

Hypersensitivity
Patch Tests
Contact Dermatitis
Denmark
Allergens
Retrospective Studies

Citer dette

Heisterberg, M. S. V., Andersen, K. E., Avnstorp, C., Kristensen, B., Kristensen, A. O., Kaaber, K., ... Johansen, J. D. (2010). Fragrance mix II in the baseline series contributes significantly to detection of fragrance allergy. Contact Dermatitis, 63(5), 270-276. https://doi.org/10.1111/j.1600-0536.2010.01737.x
Heisterberg, Maria S Vølund ; Andersen, Klaus Ejner ; Avnstorp, Christian ; Kristensen, Berit ; Kristensen, Axel Ove ; Kaaber, Knud ; Laurberg, Grete ; Menné, Torkil ; Nielsen, Niels Henrik ; Sommerlund, Mette ; Thormann, Jens ; Veien, Niels ; Vissing, Susanne ; Johansen, Jeanne Duus. / Fragrance mix II in the baseline series contributes significantly to detection of fragrance allergy. I: Contact Dermatitis. 2010 ; Bind 63, Nr. 5. s. 270-276.
@article{d191f33c555d427d8aff1ce36eceb064,
title = "Fragrance mix II in the baseline series contributes significantly to detection of fragrance allergy",
abstract = "Background: Fragrance mix II (FM II) is a relatively new screening marker for fragrance contact allergy. It was introduced in the patch test baseline series in Denmark in 2005 and contains six different fragrance chemicals commonly present in cosmetic products and which are known allergens. Aim: To investigate the diagnostic contribution of including FM II in the baseline series by comparing it with other screening markers of fragrance allergy: fragrance mix I (FM I), Myroxylon pereirae and hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC). Method: Retrospective study of 12 302 patients consecutively patch tested with FM II by members of the Danish Contact Dermatitis Group 2005-2008. Results: FM II gave a positive patch test in 553 patients (4.5{\%}), and in 72.2{\%} of these patients the reaction was judged to be clinically relevant. FM II ranked second in detecting fragrance allergy, after FM I. If FM II had not been included as a screening marker in the baseline series, 15.6{\%} (n = 202) of individuals with fragrance allergy would not have been identified by the other fragrance screening markers (FM I, M. pereirae or HICC). Conclusion: FM II contributes substantially to detecting fragrance allergy. It ranked second among the fragrance screening markers tested in the baseline series and detects individuals with an allergy who otherwise would not have been identified.",
author = "Heisterberg, {Maria S V{\o}lund} and Andersen, {Klaus Ejner} and Christian Avnstorp and Berit Kristensen and Kristensen, {Axel Ove} and Knud Kaaber and Grete Laurberg and Torkil Menn{\'e} and Nielsen, {Niels Henrik} and Mette Sommerlund and Jens Thormann and Niels Veien and Susanne Vissing and Johansen, {Jeanne Duus}",
note = "{\circledC} 2010 John Wiley & Sons A/S.",
year = "2010",
month = "11",
day = "1",
doi = "10.1111/j.1600-0536.2010.01737.x",
language = "English",
volume = "63",
pages = "270--276",
journal = "Contact Dermatitis",
issn = "0105-1873",
publisher = "Wiley-Blackwell",
number = "5",

}

Heisterberg, MSV, Andersen, KE, Avnstorp, C, Kristensen, B, Kristensen, AO, Kaaber, K, Laurberg, G, Menné, T, Nielsen, NH, Sommerlund, M, Thormann, J, Veien, N, Vissing, S & Johansen, JD 2010, 'Fragrance mix II in the baseline series contributes significantly to detection of fragrance allergy', Contact Dermatitis, bind 63, nr. 5, s. 270-276. https://doi.org/10.1111/j.1600-0536.2010.01737.x

Fragrance mix II in the baseline series contributes significantly to detection of fragrance allergy. / Heisterberg, Maria S Vølund; Andersen, Klaus Ejner; Avnstorp, Christian; Kristensen, Berit; Kristensen, Axel Ove; Kaaber, Knud; Laurberg, Grete; Menné, Torkil; Nielsen, Niels Henrik; Sommerlund, Mette; Thormann, Jens; Veien, Niels; Vissing, Susanne; Johansen, Jeanne Duus.

I: Contact Dermatitis, Bind 63, Nr. 5, 01.11.2010, s. 270-276.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Fragrance mix II in the baseline series contributes significantly to detection of fragrance allergy

AU - Heisterberg, Maria S Vølund

AU - Andersen, Klaus Ejner

AU - Avnstorp, Christian

AU - Kristensen, Berit

AU - Kristensen, Axel Ove

AU - Kaaber, Knud

AU - Laurberg, Grete

AU - Menné, Torkil

AU - Nielsen, Niels Henrik

AU - Sommerlund, Mette

AU - Thormann, Jens

AU - Veien, Niels

AU - Vissing, Susanne

AU - Johansen, Jeanne Duus

N1 - © 2010 John Wiley & Sons A/S.

PY - 2010/11/1

Y1 - 2010/11/1

N2 - Background: Fragrance mix II (FM II) is a relatively new screening marker for fragrance contact allergy. It was introduced in the patch test baseline series in Denmark in 2005 and contains six different fragrance chemicals commonly present in cosmetic products and which are known allergens. Aim: To investigate the diagnostic contribution of including FM II in the baseline series by comparing it with other screening markers of fragrance allergy: fragrance mix I (FM I), Myroxylon pereirae and hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC). Method: Retrospective study of 12 302 patients consecutively patch tested with FM II by members of the Danish Contact Dermatitis Group 2005-2008. Results: FM II gave a positive patch test in 553 patients (4.5%), and in 72.2% of these patients the reaction was judged to be clinically relevant. FM II ranked second in detecting fragrance allergy, after FM I. If FM II had not been included as a screening marker in the baseline series, 15.6% (n = 202) of individuals with fragrance allergy would not have been identified by the other fragrance screening markers (FM I, M. pereirae or HICC). Conclusion: FM II contributes substantially to detecting fragrance allergy. It ranked second among the fragrance screening markers tested in the baseline series and detects individuals with an allergy who otherwise would not have been identified.

AB - Background: Fragrance mix II (FM II) is a relatively new screening marker for fragrance contact allergy. It was introduced in the patch test baseline series in Denmark in 2005 and contains six different fragrance chemicals commonly present in cosmetic products and which are known allergens. Aim: To investigate the diagnostic contribution of including FM II in the baseline series by comparing it with other screening markers of fragrance allergy: fragrance mix I (FM I), Myroxylon pereirae and hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC). Method: Retrospective study of 12 302 patients consecutively patch tested with FM II by members of the Danish Contact Dermatitis Group 2005-2008. Results: FM II gave a positive patch test in 553 patients (4.5%), and in 72.2% of these patients the reaction was judged to be clinically relevant. FM II ranked second in detecting fragrance allergy, after FM I. If FM II had not been included as a screening marker in the baseline series, 15.6% (n = 202) of individuals with fragrance allergy would not have been identified by the other fragrance screening markers (FM I, M. pereirae or HICC). Conclusion: FM II contributes substantially to detecting fragrance allergy. It ranked second among the fragrance screening markers tested in the baseline series and detects individuals with an allergy who otherwise would not have been identified.

U2 - 10.1111/j.1600-0536.2010.01737.x

DO - 10.1111/j.1600-0536.2010.01737.x

M3 - Journal article

C2 - 20946455

VL - 63

SP - 270

EP - 276

JO - Contact Dermatitis

JF - Contact Dermatitis

SN - 0105-1873

IS - 5

ER -