First-time urea breath tests performed at home by 36,629 patients: a study of Helicobacter pylori prevalence in primary care

Søren Dahlerup, Rikke Charlotte Andersen, Birgitte Sperling Wilms Nielsen, Inger Schjødt, Lisbet Ambrosius Christensen, Ulrik Gerdes, Jens Frederik Dahlerup

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstrakt

BACKGROUND: The aim of the current study was (1) to describe the use of a (13) C-urea breath test (UBT) that was performed by patients at their homes as a part of a test-and-treat strategy in primary care and (2) to investigate the prevalence of Helicobacter pylori in patients taking a first-time UBT.

MATERIAL AND METHODS: The patients performed UBTs at home based on the discretion of the general practitioner and mailed the breath bags to a central laboratory for analysis. Each patient was identified by a unique civil registration number. The study was population-based, and the background population was approximately 700,000 people.

RESULTS: From 2003 to 2009, 44,487 UBTs were performed. Of these, 36,629 were first-time UBTs. In total, 726 of 45,213 breath bags received (1.6%) were unable to be analyzed because of errors with the bags. For both women and men who were ≤ 45 years of age, positive H. pylori declined over the time course of the study (women: 19.6% in 2003 to 17.6% in 2009, p < .01; men: 20.7% in 2003 to 16.9% in 2009, p < .001). Patients who were older than 45 years had significantly higher positive H. pylori results than younger patients.

CONCLUSIONS: A test-and-treat system was possible to implement that allowed patients to perform UBTs at their homes. The results of the first-time UBTs demonstrated that approximately one of five patients who presented with dyspepsia in the clinical setting of Danish primary care was infected with H. pylori.

OriginalsprogEngelsk
TidsskriftHelicobacter (Oxford, Online)
Vol/bind16
Udgave nummer6
Sider (fra-til)468-474
ISSN1083-4389
DOI
StatusUdgivet - dec. 2011
Udgivet eksterntJa

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