Enzymatic incorporation of LNA nucleotides into DNA strands

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Abstrakt

Unlocking uses of locked nucleic acids: LNA nucleoside 5′‐triphosphates have been synthesized, and their ability to serve as substrates for polymerases have been investigated. Phusion high‐fidelity DNA polymerase was found to be an efficient enzyme for incorporating LNA nucleoside 5′‐triphosphates into DNA strands.

OriginalsprogEngelsk
TidsskriftChemBioChem
Vol/bind8
Udgave nummer5
Sider (fra-til)490-492
ISSN1439-4227
DOI
StatusUdgivet - 2007

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