Endoskopisk ultralydskanning af maligne tumorer i øvre abdomen

M B Mortensen, C P Hovendal, S A Pedersen

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Endoscopic ultrasonography (EUS) of the upper gastrointestinal tract is a newly developed, non-invasive investigational method. It combines the direct optical picture of the endoscope with a simultaneous ultrasonographic image of the whole wall of the oesophagus, stomach and duodenum as well as organs and other structures with anatomical relations to the upper gastrointestinal tract. EUS is evaluated for its capacity with respect to cancer of the oesophagus, stomach, pancreas, biliary tree and neuroendocrine tumours, the emphasis being laid on TNM-classification, assessment of resectability and comparison with other imaging techniques. It is concluded that EUS is well-suited for assessing tumour infiltration and thereby also the resectability of these cancer types. Judging whether lymph nodes visualized by EUS are malignant or not is difficult when operating solely from endosonographic and quantitative criteria, and while the sensitivity of EUS for detecting lymph node metastases is in most situations superior to other investigational methods, the specificity and ability to visualize distant metastases is poor. For these purposes the optimal solution appears to be a combination of EUS with CT and/or ultrasound scanning. Future possibility of EUS-guided biopsy will strengthen the method's position in the diagnostic armoury concerning malignant disease in the upper gastrointestinal tract.

OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind155
Udgave nummer28
Sider (fra-til)2186-2191
ISSN0041-5782
StatusUdgivet - 12. jul. 1993

Fingeraftryk

Endosonography
Upper Gastrointestinal Tract
Neoplasms
Lymph Nodes
Neuroendocrine Tumors
Neoplasm Staging
Esophageal Neoplasms
Duodenum
Esophagus
Pancreas

Emneord

  • Digestive System Neoplasms
  • Endoscopy, Digestive System
  • Evaluation Studies as Topic
  • Humans
  • Lymph Nodes

Citer dette

Mortensen, M. B., Hovendal, C. P., & Pedersen, S. A. (1993). Endoskopisk ultralydskanning af maligne tumorer i øvre abdomen. Ugeskrift for Laeger, 155(28), 2186-2191.
Mortensen, M B ; Hovendal, C P ; Pedersen, S A. / Endoskopisk ultralydskanning af maligne tumorer i øvre abdomen. I: Ugeskrift for Laeger. 1993 ; Bind 155, Nr. 28. s. 2186-2191.
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Mortensen, MB, Hovendal, CP & Pedersen, SA 1993, 'Endoskopisk ultralydskanning af maligne tumorer i øvre abdomen', Ugeskrift for Laeger, bind 155, nr. 28, s. 2186-2191.

Endoskopisk ultralydskanning af maligne tumorer i øvre abdomen. / Mortensen, M B; Hovendal, C P; Pedersen, S A.

I: Ugeskrift for Laeger, Bind 155, Nr. 28, 12.07.1993, s. 2186-2191.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Endoskopisk ultralydskanning af maligne tumorer i øvre abdomen

AU - Mortensen, M B

AU - Hovendal, C P

AU - Pedersen, S A

PY - 1993/7/12

Y1 - 1993/7/12

N2 - Endoscopic ultrasonography (EUS) of the upper gastrointestinal tract is a newly developed, non-invasive investigational method. It combines the direct optical picture of the endoscope with a simultaneous ultrasonographic image of the whole wall of the oesophagus, stomach and duodenum as well as organs and other structures with anatomical relations to the upper gastrointestinal tract. EUS is evaluated for its capacity with respect to cancer of the oesophagus, stomach, pancreas, biliary tree and neuroendocrine tumours, the emphasis being laid on TNM-classification, assessment of resectability and comparison with other imaging techniques. It is concluded that EUS is well-suited for assessing tumour infiltration and thereby also the resectability of these cancer types. Judging whether lymph nodes visualized by EUS are malignant or not is difficult when operating solely from endosonographic and quantitative criteria, and while the sensitivity of EUS for detecting lymph node metastases is in most situations superior to other investigational methods, the specificity and ability to visualize distant metastases is poor. For these purposes the optimal solution appears to be a combination of EUS with CT and/or ultrasound scanning. Future possibility of EUS-guided biopsy will strengthen the method's position in the diagnostic armoury concerning malignant disease in the upper gastrointestinal tract.

AB - Endoscopic ultrasonography (EUS) of the upper gastrointestinal tract is a newly developed, non-invasive investigational method. It combines the direct optical picture of the endoscope with a simultaneous ultrasonographic image of the whole wall of the oesophagus, stomach and duodenum as well as organs and other structures with anatomical relations to the upper gastrointestinal tract. EUS is evaluated for its capacity with respect to cancer of the oesophagus, stomach, pancreas, biliary tree and neuroendocrine tumours, the emphasis being laid on TNM-classification, assessment of resectability and comparison with other imaging techniques. It is concluded that EUS is well-suited for assessing tumour infiltration and thereby also the resectability of these cancer types. Judging whether lymph nodes visualized by EUS are malignant or not is difficult when operating solely from endosonographic and quantitative criteria, and while the sensitivity of EUS for detecting lymph node metastases is in most situations superior to other investigational methods, the specificity and ability to visualize distant metastases is poor. For these purposes the optimal solution appears to be a combination of EUS with CT and/or ultrasound scanning. Future possibility of EUS-guided biopsy will strengthen the method's position in the diagnostic armoury concerning malignant disease in the upper gastrointestinal tract.

KW - Digestive System Neoplasms

KW - Endoscopy, Digestive System

KW - Evaluation Studies as Topic

KW - Humans

KW - Lymph Nodes

M3 - Tidsskriftartikel

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JO - Ugeskrift for Laeger

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