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Encapsulation of the HDACi Ex527 into liposomes and polymer-based particles

  • Dorle Hennig
  • , Diana Imhof*
  • *Kontaktforfatter
    • University of Bonn

    Publikation: Kapitel i bog/rapport/konference-proceedingKapitel i bogForskningpeer review

    Abstract

    Incorporation of drugs into particles can improve their therapeutic effectiveness. Solubility, half-life time, targeting, and the release of the drug can be modified by the encapsulation into a particle. Histone deacetylase inhibitors have a great potential to be used as therapeutics for many different diseases. In this chapter, we describe the inclusion of the low molar mass HDACi Ex527 into polymer-based particles and liposomes.

    OriginalsprogEngelsk
    TitelHDAC/HAT Function Assessment and Inhibitor Development
    RedaktørerOliver H. Krämer
    Vol/bind1510
    ForlagSpringer
    Publikationsdato2017
    Sider387-398
    Kapitel29
    ISBN (Trykt)9781493965250
    ISBN (Elektronisk)9781493965274
    DOI
    StatusUdgivet - 2017
    NavnMethods in Molecular Biology
    Vol/bind1510
    ISSN1064-3745

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