Encapsulation of the HDACi Ex527 into liposomes and polymer-based particles

Dorle Hennig, Diana Imhof*

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Publikation: Kapitel i bog/rapport/konference-proceedingKapitel i bogForskningpeer review

Abstrakt

Incorporation of drugs into particles can improve their therapeutic effectiveness. Solubility, half-life time, targeting, and the release of the drug can be modified by the encapsulation into a particle. Histone deacetylase inhibitors have a great potential to be used as therapeutics for many different diseases. In this chapter, we describe the inclusion of the low molar mass HDACi Ex527 into polymer-based particles and liposomes.

OriginalsprogEngelsk
TitelHDAC/HAT Function Assessment and Inhibitor Development
RedaktørerOliver H. Krämer
Vol/bind1510
ForlagSpringer
Publikationsdato2017
Sider387-398
Kapitel29
ISBN (Trykt)9781493965250
ISBN (Elektronisk)9781493965274
DOI
StatusUdgivet - 2017
NavnMethods in Molecular Biology
Vol/bind1510
ISSN1064-3745

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