@article{de5e9c90ba9811dc9626000ea68e967b,
title = "Electron Capture Dissociation of Weakly Bound Polypeptide Polycationic Complexes",
abstract = "We have previously reported that, in electron capture dissociation (ECD), rupture of strong intramolecular bonds in weakly bound supramolecular aggregates can proceed without dissociation of weak intermolecular bonds. This is now illustrated on a series of non-specific peptide-peptide dimers as well as specific complexes of modified glycopeptide antibiotics with their target peptide. The weak nature of bonding is substantiated by blackbody infrared dissociation, low-energy collisional excitation and force-field simulations. The results are consistent with a non-ergodic ECD cleavage mechanism.",
keywords = "Anti-Bacterial Agents, Cations, Chemistry, Physical, Dimerization, Electrons, Glycopeptides, Hydrogen Bonding, Mass Spectrometry, Molecular Structure, Peptides, Vancomycin",
author = "Haselmann, {Kim F} and J{\o}rgensen, {Thomas J D} and Budnik, {Bogdan A} and Frank Jensen and Zubarev, {Roman A}",
note = "Copyright 2002 John Wiley & Sons, Ltd.",
year = "2002",
doi = "10.1002/rcm.853",
language = "English",
volume = "16",
pages = "2260--5",
journal = "Rapid Communications in Mass Spectrometry",
issn = "0951-4198",
publisher = "Wiley",
number = "24",
}