Eight weeks of mineralocorticoid blockade does not improve insulin sensitivity in type 2 diabetes

Stine Louise Høyer Finsen, Mie R. Hansen, Joachim Hoffmann-Petersen, Henrik F. Højgaard, Stefan P. Mortensen

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstrakt

Abstract Individuals with type 2 diabetes have an increased risk of cardiovascular disease. A correlation between plasma aldosterone and hyperinsulinemia has been demonstrated in vivo, and hyperinsulinemia and insulin resistance are independently associated with the development of cardiovascular complications. We investigated if mineralocorticoid blockade (Eplerenone) improves insulin sensitivity in individuals with type 2 diabetes compared to healthy controls. We included 13 participants with type 2 diabetes (
OriginalsprogEngelsk
Artikelnummere14971
TidsskriftPhysiological Reports
Vol/bind9
Udgave nummer15
ISSN2051-817X
DOI
StatusUdgivet - aug. 2021

Bibliografisk note

https://doi.org/10.14814/phy2.14971

Emneord

  • aldosterone
  • insulin sensitivity
  • mineralocorticoid blockade
  • type 2 diabetes

Fingeraftryk

Dyk ned i forskningsemnerne om 'Eight weeks of mineralocorticoid blockade does not improve insulin sensitivity in type 2 diabetes'. Sammen danner de et unikt fingeraftryk.

Citationsformater