Effects of extracellular osmolality on renin release and on the ultrastructure of the juxtaglomerular epithelioid cell granules

O Skøtt, R Taugner

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Abstrakt

Superfusion with hypoosmotic solutions stimulates renin release from rat epithelioid cells adherent to isolated glomeruli. This stimulatory effect may be related to the observed swelling of the secretory granules; the swelling may markedly increase the probability of pre-exocytotic fusions between the granule and cell membranes, and consequently increase the frequency of exocytotic events.

OriginalsprogEngelsk
TidsskriftCell and Tissue Research
Vol/bind249
Udgave nummer2
Sider (fra-til)325-9
Antal sider5
ISSN0302-766X
StatusUdgivet - aug. 1987

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