Effect of the SK/IK channel modulator 4,5-dichloro-1,3-diethyl-1,3-dihydro-benzoimidazol-2-one (NS4591) on contractile force in rat, pig and human detrusor smooth muscle

Jens Steen Nielsen, Frederik Rode, Mette Rahbek, Karl-Erik Andersson, Lars Christian Rønn, Kirsten Bouchelouche, Jorgen Nordling, Pierre Bouchelouche

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstrakt

• To investigate the importance of small (SK)- and intermediate (IK)-conductance Ca2(+) -activated K(+) channels on bladder function, by studying the effects of 4,5-dichloro-1,3-diethyl-1,3-dihydro-benzoimidazol-2-one (NS4591), a new modulator of SK/IK channels, on contractions induced by electrical field stimulation (EFS) and carbachol in rat, pig and human detrusor.
OriginalsprogEngelsk
TidsskriftB J U International (Print)
Vol/bind108
Udgave nummer5
Sider (fra-til)771-7
Antal sider7
ISSN1464-4096
DOI
StatusUdgivet - 2011

Fingeraftryk Dyk ned i forskningsemnerne om 'Effect of the SK/IK channel modulator 4,5-dichloro-1,3-diethyl-1,3-dihydro-benzoimidazol-2-one (NS4591) on contractile force in rat, pig and human detrusor smooth muscle'. Sammen danner de et unikt fingeraftryk.

Citationsformater