Effect of sex, age, and race on the clinical presentation of tuberculosis: a 15-year population-based study

Xinyu Zhang, Åse Bengård Andersen, Troels Lillebaek, Zaza Kamper-Jørgensen, Vibeke Østergaard Thomsen, Karin Ladefoged, Carl F Marrs, Lixin Zhang, Zhenhua Yang

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Abstrakt

Extrapulmonary tuberculosis (EPTB) is an important health problem that may cause serious morbidity and diagnostic challenges. We conducted a case-control study involving 5,684, approximately 99% of bacteriologically confirmed TB patients (including 1,925 EPTB cases) diagnosed in Denmark and Greenland during 1992-2007 to gain insight to the role of host factors in EPTB pathogenesis. Among patients from Somalia and Asia, persons 25-44 and 45-64 years of age were more likely to have EPTB than persons 15-24 years of age. In contrast, among persons from Greenland, the two oldest age groups were significantly less likely to have EPTB than the youngest age group. For all the age groups, the odds for having EPTB was significantly higher among patients from Somalia and Asia and significantly lower among the patients from Greenland than among patients from Denmark. Furthermore, the occurrence of specific types of EPTB significantly varied among different age groups or origins.
OriginalsprogEngelsk
TidsskriftAmerican Journal of Tropical Medicine and Hygiene
Vol/bind85
Udgave nummer2
Sider (fra-til)285-90
Antal sider6
ISSN0002-9637
DOI
StatusUdgivet - 2011

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