Background: In patients with critical leg ischemia (CLI), the standard operative choice is an in situ bypass to the lower extremity to improve the patients´ prognosis and quality of life. Postoperative complications after surgery occur in 18 % of the patients, prolonging hospitalization and convalescence. The main operative complication is edema. This can be prevented by early mobilization or stimulation of the natural venous pump in the leg. Objective: To investigate whether compression therapy with foot pump reduces postoperative edema, facilitates wound healing of the operation wounds, promotes healing of ischemic ulcers, and shortens hospitalization, increasing and improving the patient’s subjective quality of life faster. Methods: The protocol is designed as a randomized, unblinded prospective study with 50 patients in each group. Standard postoperative routines after bypass surgery, including short-stretch bandaging of the operated legs, are compared to supportive stimulation of the venous pump by an impulsive compression foot pump. The postoperative edema of the leg is measured 10 cm below the patella and 8 cm proximal to the medial malleolus. Measurements are performed preoperatively, 1 and 4 days postoperatively and at discharge. Results: The primary endpoint is reduction of leg edema by at least 50%. The secondary endpoint includes earlier mobilization in the pump group and decreased length of stay in hospital. Quality of life is evaluated through the European Health Related Quality of Life Questionnaire 5 Dimensions (EQ-5D) and Vascular Quality of Life Questionnaire-6 (VascuQol-6) questionnaires. The start of the study is February 1, 2018, and the end of the study is February 1, 2020. First results will be available April 2020. Conclusions: In orthopedic surgery of the lower extremities, the use of foot pumps has shown a reduction of edema and thrombosis in risk patients. Although important positive effects may be expected after vein bypass surgery, no reports have yet investigated the use of the device in vascular-operated patients and no analysis or meta Cochrane reviews are available in this field.
Bibliografisk noteFunding Information:
The authors acknowledge the financial support of the project initiator, Hans Ravn, Chief MD, Department of Vascular Surgery, Hospital Lillebaelt, Denmark. They also recognize the support of theaccount at Department of Vascular Surgery, Hospital Lillebaelt, Denmark and unrestricted grants. Independent, disposable materials associated with the use of foot pumps will be bought and paid for by the Department of Vascular Surgery. As described above, we are continuing the process of seeking funds for the trial. Covidien does not influence the design of the protocol or analysis, interpretation, and publication of results. The collection of data was performed by TK. Management of data was performed by TK, MD, and HR. Analysis of data was performed by TK, MD, KH, and HR. Interpretation of data was performed by TK, MD, KH, and HR. The report was written by TK, MD, KH, and HR. The decision to submit the report for publication was made by KH and HR. TK, KH, HR are members of the steering committee.
©Tenna Klit, Marie Dahl, Kim Christian Houlind, Hans Ravn.
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