Effect of dietary fatty acid intake on prospective weight change in the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition

Katharina Nimptsch, Gabi Berg-Beckhoff, Jakob Linseisen

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

OBJECTIVE: To evaluate the association between fatty acid (alpha-linolenic acid (ALA), EPA, DHA, palmitic, stearic, oleic, linoleic and arachidonic acids) intake and prospective weight change in the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition. DESIGN: Prospective cohort study with mean follow-up time of 6.5 years. In a total of 9182 men and 10867 women aged 35 to 64 years, from body weight measurement at recruitment and calibrated body weight during follow-up, weight change was expressed as mean annual weight change relative to baseline weight (%/year) and categorised into four groups (weight loss, or =2.5 to or =7.5%/5 years). Energy-adjusted dietary fatty acid intake data were estimated from the FFQ completed at baseline. Multivariate linear regression models as well as multinomial logistic regression analyses (carbohydrate replacement models) were conducted. RESULTS: Stearic acid intake was linearly associated with weight gain (P <0.01) in men and women. Linear associations also existed for ALA and arachidonic acid intake, significantly so in women. In multinomial models, women in the highest tertile of ALA and stearic acid intake showed increased OR (95 % CI) for small weight gain (1.16 (0.94, 1.88) and 1.24 (1.08, 1.43), respectively), and large weight gain (1.39 (1.03, 1.88) and 1.56 (1.27, 1.90), respectively), whereas OR were non-significantly increased in men. Dietary intake of ALA was inversely associated with large (0.80 (0.65, 0.99)) weight gain in women only. CONCLUSIONS: These results suggest differential effects of single dietary fatty acids on prospective weight gain in adults.
OriginalsprogEngelsk
TidsskriftPublic Health Nutrition
Vol/bind13
Udgave nummer10
Sider (fra-til)1636-46
Antal sider11
ISSN1368-9800
DOI
StatusUdgivet - 1. okt. 2010

Fingeraftryk

alpha-Linolenic Acid
Weight Gain
Fatty Acids
Weights and Measures
Neoplasms
Linear Models
Arachidonic Acid
Cohort Studies
Logistic Models
Regression Analysis
Prospective Studies

Citer dette

@article{f365fff3a1b34fd5bea40659836f0d79,
title = "Effect of dietary fatty acid intake on prospective weight change in the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition",
abstract = "OBJECTIVE: To evaluate the association between fatty acid (alpha-linolenic acid (ALA), EPA, DHA, palmitic, stearic, oleic, linoleic and arachidonic acids) intake and prospective weight change in the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition. DESIGN: Prospective cohort study with mean follow-up time of 6.5 years. In a total of 9182 men and 10867 women aged 35 to 64 years, from body weight measurement at recruitment and calibrated body weight during follow-up, weight change was expressed as mean annual weight change relative to baseline weight ({\%}/year) and categorised into four groups (weight loss, or =2.5 to or =7.5{\%}/5 years). Energy-adjusted dietary fatty acid intake data were estimated from the FFQ completed at baseline. Multivariate linear regression models as well as multinomial logistic regression analyses (carbohydrate replacement models) were conducted. RESULTS: Stearic acid intake was linearly associated with weight gain (P <0.01) in men and women. Linear associations also existed for ALA and arachidonic acid intake, significantly so in women. In multinomial models, women in the highest tertile of ALA and stearic acid intake showed increased OR (95 {\%} CI) for small weight gain (1.16 (0.94, 1.88) and 1.24 (1.08, 1.43), respectively), and large weight gain (1.39 (1.03, 1.88) and 1.56 (1.27, 1.90), respectively), whereas OR were non-significantly increased in men. Dietary intake of ALA was inversely associated with large (0.80 (0.65, 0.99)) weight gain in women only. CONCLUSIONS: These results suggest differential effects of single dietary fatty acids on prospective weight gain in adults.",
author = "Katharina Nimptsch and Gabi Berg-Beckhoff and Jakob Linseisen",
year = "2010",
month = "10",
day = "1",
doi = "10.1017/S1368980009993041",
language = "English",
volume = "13",
pages = "1636--46",
journal = "Public Health Nutrition",
issn = "1368-9800",
publisher = "Heinemann",
number = "10",

}

Effect of dietary fatty acid intake on prospective weight change in the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition. / Nimptsch, Katharina; Berg-Beckhoff, Gabi; Linseisen, Jakob.

I: Public Health Nutrition, Bind 13, Nr. 10, 01.10.2010, s. 1636-46.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Effect of dietary fatty acid intake on prospective weight change in the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition

AU - Nimptsch, Katharina

AU - Berg-Beckhoff, Gabi

AU - Linseisen, Jakob

PY - 2010/10/1

Y1 - 2010/10/1

N2 - OBJECTIVE: To evaluate the association between fatty acid (alpha-linolenic acid (ALA), EPA, DHA, palmitic, stearic, oleic, linoleic and arachidonic acids) intake and prospective weight change in the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition. DESIGN: Prospective cohort study with mean follow-up time of 6.5 years. In a total of 9182 men and 10867 women aged 35 to 64 years, from body weight measurement at recruitment and calibrated body weight during follow-up, weight change was expressed as mean annual weight change relative to baseline weight (%/year) and categorised into four groups (weight loss, or =2.5 to or =7.5%/5 years). Energy-adjusted dietary fatty acid intake data were estimated from the FFQ completed at baseline. Multivariate linear regression models as well as multinomial logistic regression analyses (carbohydrate replacement models) were conducted. RESULTS: Stearic acid intake was linearly associated with weight gain (P <0.01) in men and women. Linear associations also existed for ALA and arachidonic acid intake, significantly so in women. In multinomial models, women in the highest tertile of ALA and stearic acid intake showed increased OR (95 % CI) for small weight gain (1.16 (0.94, 1.88) and 1.24 (1.08, 1.43), respectively), and large weight gain (1.39 (1.03, 1.88) and 1.56 (1.27, 1.90), respectively), whereas OR were non-significantly increased in men. Dietary intake of ALA was inversely associated with large (0.80 (0.65, 0.99)) weight gain in women only. CONCLUSIONS: These results suggest differential effects of single dietary fatty acids on prospective weight gain in adults.

AB - OBJECTIVE: To evaluate the association between fatty acid (alpha-linolenic acid (ALA), EPA, DHA, palmitic, stearic, oleic, linoleic and arachidonic acids) intake and prospective weight change in the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition. DESIGN: Prospective cohort study with mean follow-up time of 6.5 years. In a total of 9182 men and 10867 women aged 35 to 64 years, from body weight measurement at recruitment and calibrated body weight during follow-up, weight change was expressed as mean annual weight change relative to baseline weight (%/year) and categorised into four groups (weight loss, or =2.5 to or =7.5%/5 years). Energy-adjusted dietary fatty acid intake data were estimated from the FFQ completed at baseline. Multivariate linear regression models as well as multinomial logistic regression analyses (carbohydrate replacement models) were conducted. RESULTS: Stearic acid intake was linearly associated with weight gain (P <0.01) in men and women. Linear associations also existed for ALA and arachidonic acid intake, significantly so in women. In multinomial models, women in the highest tertile of ALA and stearic acid intake showed increased OR (95 % CI) for small weight gain (1.16 (0.94, 1.88) and 1.24 (1.08, 1.43), respectively), and large weight gain (1.39 (1.03, 1.88) and 1.56 (1.27, 1.90), respectively), whereas OR were non-significantly increased in men. Dietary intake of ALA was inversely associated with large (0.80 (0.65, 0.99)) weight gain in women only. CONCLUSIONS: These results suggest differential effects of single dietary fatty acids on prospective weight gain in adults.

U2 - 10.1017/S1368980009993041

DO - 10.1017/S1368980009993041

M3 - Journal article

VL - 13

SP - 1636

EP - 1646

JO - Public Health Nutrition

JF - Public Health Nutrition

SN - 1368-9800

IS - 10

ER -