Resumé
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | Adverse Drug Reaction Bulletin |
| Vol/bind | 313 |
| Udgave nummer | 1 |
| Sider (fra-til) | 1211–1214 |
| ISSN | 0044-6394 |
| DOI | |
| Status | Udgivet - dec. 2018 |
Fingeraftryk
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Drug-induced Sialorrhoea. / Haastrup, Maija Bruun; Henriksen, Daniel Pilsgaard; Christensen, Mette Marie.
I: Adverse Drug Reaction Bulletin, Bind 313, Nr. 1, 12.2018, s. 1211–1214.Publikation: Bidrag til tidsskrift › Review › Forskning › peer review
TY - JOUR
T1 - Drug-induced Sialorrhoea
AU - Haastrup, Maija Bruun
AU - Henriksen, Daniel Pilsgaard
AU - Christensen, Mette Marie
PY - 2018/12
Y1 - 2018/12
N2 - Sialorrhoea is a common adverse effect of a range of medicines, primarily clozapine. At least a third of patients treated with clozapine suffer from sialorrhoea, and the consequences of this can be socially stigmatising and lead to non-adherence. The treatment options are limited and primarily centered around muscarinic antagonism. We suggest non-pharmacological interventions followed by locally applied atropine or glycopyrrolate. If systemic treatment is necessary, amisulpride, benztropine, or terazosin may be attempted.
AB - Sialorrhoea is a common adverse effect of a range of medicines, primarily clozapine. At least a third of patients treated with clozapine suffer from sialorrhoea, and the consequences of this can be socially stigmatising and lead to non-adherence. The treatment options are limited and primarily centered around muscarinic antagonism. We suggest non-pharmacological interventions followed by locally applied atropine or glycopyrrolate. If systemic treatment is necessary, amisulpride, benztropine, or terazosin may be attempted.
U2 - 10.1097/FAD.0000000000000037
DO - 10.1097/FAD.0000000000000037
M3 - Review
VL - 313
SP - 1211
EP - 1214
JO - Adverse Drug Reaction Bulletin
JF - Adverse Drug Reaction Bulletin
SN - 0044-6394
IS - 1
ER -