Do patients initiate therapy?

Primary non-adherence to statins and antidepressants in Iceland

G Thengilsdóttir, Anton Pottegård, K Linnet, M Halldórsson, A B Almarsdóttir, H Gardarsdóttir

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

BACKGROUND: Primary non-adherence occurs when a drug has been prescribed but the patient fails to have it dispensed at the pharmacy.

AIMS: To assess primary non-adherence to statins and antidepressants in Iceland, the association of demographic factors with primary non-adherence, and the time from when a prescription is issued until it is dispensed.

METHODS: Data on patients receiving a new prescription for a statin or an antidepressant from the Primary Health Care database were linked with dispensing histories from The Icelandic Prescription Database. The proportion of patients who did not have their prescription dispensed within a year from issuing (primary non-adherent) was assessed, as well as the time from issue until dispensing. Associations between demographic factors and primary non-adherence were estimated using logistic regression.

RESULTS: The overall primary non-adherence was 6.3% and 8.0% for statins and antidepressants, respectively. The majority of patients had their prescription dispensed within 7 days (85% for statins, 87% for antidepressants). Being disabled and receiving a prescription for an expensive drug was associated with higher rates of primary non-adherence.

CONCLUSION: The rate of primary non-adherence to statins and antidepressants in Iceland is low. Vulnerable groups such as the disabled should be given special attention when new drugs are prescribed.

OriginalsprogEngelsk
TidsskriftInternational Journal of Clinical Practice
Vol/bind69
Udgave nummer5
Sider (fra-til)597-603
ISSN1368-5031
DOI
StatusUdgivet - maj 2015

Fingeraftryk

Iceland
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Prescriptions
Databases
Pharmaceutical Preparations
Primary Health Care
Logistic Models

Citer dette

Thengilsdóttir, G ; Pottegård, Anton ; Linnet, K ; Halldórsson, M ; Almarsdóttir, A B ; Gardarsdóttir, H. / Do patients initiate therapy? Primary non-adherence to statins and antidepressants in Iceland. I: International Journal of Clinical Practice. 2015 ; Bind 69, Nr. 5. s. 597-603.
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abstract = "BACKGROUND: Primary non-adherence occurs when a drug has been prescribed but the patient fails to have it dispensed at the pharmacy.AIMS: To assess primary non-adherence to statins and antidepressants in Iceland, the association of demographic factors with primary non-adherence, and the time from when a prescription is issued until it is dispensed.METHODS: Data on patients receiving a new prescription for a statin or an antidepressant from the Primary Health Care database were linked with dispensing histories from The Icelandic Prescription Database. The proportion of patients who did not have their prescription dispensed within a year from issuing (primary non-adherent) was assessed, as well as the time from issue until dispensing. Associations between demographic factors and primary non-adherence were estimated using logistic regression.RESULTS: The overall primary non-adherence was 6.3{\%} and 8.0{\%} for statins and antidepressants, respectively. The majority of patients had their prescription dispensed within 7 days (85{\%} for statins, 87{\%} for antidepressants). Being disabled and receiving a prescription for an expensive drug was associated with higher rates of primary non-adherence.CONCLUSION: The rate of primary non-adherence to statins and antidepressants in Iceland is low. Vulnerable groups such as the disabled should be given special attention when new drugs are prescribed.",
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Thengilsdóttir, G, Pottegård, A, Linnet, K, Halldórsson, M, Almarsdóttir, AB & Gardarsdóttir, H 2015, 'Do patients initiate therapy? Primary non-adherence to statins and antidepressants in Iceland', International Journal of Clinical Practice, bind 69, nr. 5, s. 597-603. https://doi.org/10.1111/ijcp.12558

Do patients initiate therapy? Primary non-adherence to statins and antidepressants in Iceland. / Thengilsdóttir, G; Pottegård, Anton; Linnet, K; Halldórsson, M; Almarsdóttir, A B; Gardarsdóttir, H.

I: International Journal of Clinical Practice, Bind 69, Nr. 5, 05.2015, s. 597-603.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Do patients initiate therapy?

T2 - Primary non-adherence to statins and antidepressants in Iceland

AU - Thengilsdóttir, G

AU - Pottegård, Anton

AU - Linnet, K

AU - Halldórsson, M

AU - Almarsdóttir, A B

AU - Gardarsdóttir, H

N1 - © 2015 John Wiley & Sons Ltd.

PY - 2015/5

Y1 - 2015/5

N2 - BACKGROUND: Primary non-adherence occurs when a drug has been prescribed but the patient fails to have it dispensed at the pharmacy.AIMS: To assess primary non-adherence to statins and antidepressants in Iceland, the association of demographic factors with primary non-adherence, and the time from when a prescription is issued until it is dispensed.METHODS: Data on patients receiving a new prescription for a statin or an antidepressant from the Primary Health Care database were linked with dispensing histories from The Icelandic Prescription Database. The proportion of patients who did not have their prescription dispensed within a year from issuing (primary non-adherent) was assessed, as well as the time from issue until dispensing. Associations between demographic factors and primary non-adherence were estimated using logistic regression.RESULTS: The overall primary non-adherence was 6.3% and 8.0% for statins and antidepressants, respectively. The majority of patients had their prescription dispensed within 7 days (85% for statins, 87% for antidepressants). Being disabled and receiving a prescription for an expensive drug was associated with higher rates of primary non-adherence.CONCLUSION: The rate of primary non-adherence to statins and antidepressants in Iceland is low. Vulnerable groups such as the disabled should be given special attention when new drugs are prescribed.

AB - BACKGROUND: Primary non-adherence occurs when a drug has been prescribed but the patient fails to have it dispensed at the pharmacy.AIMS: To assess primary non-adherence to statins and antidepressants in Iceland, the association of demographic factors with primary non-adherence, and the time from when a prescription is issued until it is dispensed.METHODS: Data on patients receiving a new prescription for a statin or an antidepressant from the Primary Health Care database were linked with dispensing histories from The Icelandic Prescription Database. The proportion of patients who did not have their prescription dispensed within a year from issuing (primary non-adherent) was assessed, as well as the time from issue until dispensing. Associations between demographic factors and primary non-adherence were estimated using logistic regression.RESULTS: The overall primary non-adherence was 6.3% and 8.0% for statins and antidepressants, respectively. The majority of patients had their prescription dispensed within 7 days (85% for statins, 87% for antidepressants). Being disabled and receiving a prescription for an expensive drug was associated with higher rates of primary non-adherence.CONCLUSION: The rate of primary non-adherence to statins and antidepressants in Iceland is low. Vulnerable groups such as the disabled should be given special attention when new drugs are prescribed.

U2 - 10.1111/ijcp.12558

DO - 10.1111/ijcp.12558

M3 - Journal article

VL - 69

SP - 597

EP - 603

JO - International Journal of Clinical Practice

JF - International Journal of Clinical Practice

SN - 1368-5031

IS - 5

ER -