DNA Self-Assembly and Computation Studied with a Coarse-grained Dynamic Bonded Model

Publikation: Kapitel i bog/rapport/konference-proceedingKonferencebidrag i proceedingsForskningpeer review

564 Downloads (Pure)

Abstrakt

We utilize a coarse-grained directional dynamic bonding DNA model [C. Svaneborg, Comp. Phys. Comm. (In Press DOI:10.1016/j.cpc.2012.03.005)] to study DNA self-assembly and DNA computation. In our DNA model, a single nucleotide is represented by a single interaction site, and complementary sites can hybridize reversibly. Along with the dynamic hybridization bonds, angular and dihedral bonds are dynamically introduced and removed to model the collective properties of double helix structure on the DNA zippering dynamics. We use this DNA model to simulate the temperature dependent self-assembly of DNA tetrahedra at several temperatures, a DNA icosahedron, and also strand displacement operations used in DNA computation.
OriginalsprogEngelsk
TitelDNA Computing and Molecular Programming
ForlagSpringer
Publikationsdato2012
Sider123-134
ISBN (Trykt)978-3-642-32207-5
ISBN (Elektronisk)978-3-642-32208-2
DOI
StatusUdgivet - 2012
BegivenhedInternational Conference on DNA Computing and Molecular Programming - Århus, Danmark
Varighed: 14. aug. 201217. aug. 2012

Konference

KonferenceInternational Conference on DNA Computing and Molecular Programming
Land/OmrådeDanmark
ByÅrhus
Periode14/08/201217/08/2012
NavnLecture Notes in Computer Science
Vol/bind7433
ISSN0302-9743

Fingeraftryk

Dyk ned i forskningsemnerne om 'DNA Self-Assembly and Computation Studied with a Coarse-grained Dynamic Bonded Model'. Sammen danner de et unikt fingeraftryk.

Citationsformater