Different meaning of the p-value in exploratory and confirmatory hypothesis testing

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Abstrakt

The outcome of clinical studies is often reduced to the statistical significance of results by indicating a p-value below the 5% significance level. Hypothesis testing and, through that, the p-value is commonly used, but their meaning is frequently misinterpreted in clinical research. The concept of hypothesis testing is explained and some pitfalls including those of multiple testing are given. The conceptual difference between exploratory and confirmatory hypothesis testing is discussed, and a better use of p-values, which includes presenting p-values with two or three decimals, is suggested.
Bidragets oversatte titel[Different meaning of the p-value in exploratory and confirmatory hypothesis testing.]
OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind173
Udgave nummer37
Sider (fra-til)2261-2264
Antal sider4
ISSN0041-5782
StatusUdgivet - 2011

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