Different Immunological Phenotypes Associated with Preserved CD4+ T Cell Counts in HIV-Infected Controllers and Viremic Long Term Non-Progressors

Julie Christine Gaardbo, Hans Jakob Hartling, Andreas Ronit, Kristina Thorsteinsson, Hans Ole Madsen, Karoline Springborg, Lise Mette Rahbek Gjerdrum, Carsten Birch, Matthew James Laye, Henrik Ullum, Ase Bengaard Andersen, Susanne Dam Nielsen

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

HIV-infected controllers control viral replication and maintain normal CD4+ T cell counts. Long Term Non-Progressors (LTNP) also maintain normal CD4+ T cell counts, but have on-going viral replication. We hypothesized that different immunological mechanisms are responsible for preserved CD4+ T cell counts in controllers and LTNP.
OriginalsprogEngelsk
TidsskriftP L o S One
Vol/bind8
Udgave nummer5
Sider (fra-til)e63744
ISSN1932-6203
DOI
StatusUdgivet - 2013

Fingeraftryk

T-cells
controllers
T-lymphocytes
HIV
virus replication
phenotype
Controllers

Citer dette

Gaardbo, J. C., Hartling, H. J., Ronit, A., Thorsteinsson, K., Madsen, H. O., Springborg, K., ... Nielsen, S. D. (2013). Different Immunological Phenotypes Associated with Preserved CD4+ T Cell Counts in HIV-Infected Controllers and Viremic Long Term Non-Progressors. P L o S One, 8(5), e63744. https://doi.org/10.1371/journal.pone.0063744
Gaardbo, Julie Christine ; Hartling, Hans Jakob ; Ronit, Andreas ; Thorsteinsson, Kristina ; Madsen, Hans Ole ; Springborg, Karoline ; Gjerdrum, Lise Mette Rahbek ; Birch, Carsten ; Laye, Matthew James ; Ullum, Henrik ; Andersen, Ase Bengaard ; Nielsen, Susanne Dam. / Different Immunological Phenotypes Associated with Preserved CD4+ T Cell Counts in HIV-Infected Controllers and Viremic Long Term Non-Progressors. I: P L o S One. 2013 ; Bind 8, Nr. 5. s. e63744.
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title = "Different Immunological Phenotypes Associated with Preserved CD4+ T Cell Counts in HIV-Infected Controllers and Viremic Long Term Non-Progressors",
abstract = "HIV-infected controllers control viral replication and maintain normal CD4+ T cell counts. Long Term Non-Progressors (LTNP) also maintain normal CD4+ T cell counts, but have on-going viral replication. We hypothesized that different immunological mechanisms are responsible for preserved CD4+ T cell counts in controllers and LTNP.",
author = "Gaardbo, {Julie Christine} and Hartling, {Hans Jakob} and Andreas Ronit and Kristina Thorsteinsson and Madsen, {Hans Ole} and Karoline Springborg and Gjerdrum, {Lise Mette Rahbek} and Carsten Birch and Laye, {Matthew James} and Henrik Ullum and Andersen, {Ase Bengaard} and Nielsen, {Susanne Dam}",
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Gaardbo, JC, Hartling, HJ, Ronit, A, Thorsteinsson, K, Madsen, HO, Springborg, K, Gjerdrum, LMR, Birch, C, Laye, MJ, Ullum, H, Andersen, AB & Nielsen, SD 2013, 'Different Immunological Phenotypes Associated with Preserved CD4+ T Cell Counts in HIV-Infected Controllers and Viremic Long Term Non-Progressors', P L o S One, bind 8, nr. 5, s. e63744. https://doi.org/10.1371/journal.pone.0063744

Different Immunological Phenotypes Associated with Preserved CD4+ T Cell Counts in HIV-Infected Controllers and Viremic Long Term Non-Progressors. / Gaardbo, Julie Christine; Hartling, Hans Jakob; Ronit, Andreas; Thorsteinsson, Kristina; Madsen, Hans Ole; Springborg, Karoline; Gjerdrum, Lise Mette Rahbek; Birch, Carsten; Laye, Matthew James; Ullum, Henrik; Andersen, Ase Bengaard; Nielsen, Susanne Dam.

I: P L o S One, Bind 8, Nr. 5, 2013, s. e63744.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Different Immunological Phenotypes Associated with Preserved CD4+ T Cell Counts in HIV-Infected Controllers and Viremic Long Term Non-Progressors

AU - Gaardbo, Julie Christine

AU - Hartling, Hans Jakob

AU - Ronit, Andreas

AU - Thorsteinsson, Kristina

AU - Madsen, Hans Ole

AU - Springborg, Karoline

AU - Gjerdrum, Lise Mette Rahbek

AU - Birch, Carsten

AU - Laye, Matthew James

AU - Ullum, Henrik

AU - Andersen, Ase Bengaard

AU - Nielsen, Susanne Dam

PY - 2013

Y1 - 2013

N2 - HIV-infected controllers control viral replication and maintain normal CD4+ T cell counts. Long Term Non-Progressors (LTNP) also maintain normal CD4+ T cell counts, but have on-going viral replication. We hypothesized that different immunological mechanisms are responsible for preserved CD4+ T cell counts in controllers and LTNP.

AB - HIV-infected controllers control viral replication and maintain normal CD4+ T cell counts. Long Term Non-Progressors (LTNP) also maintain normal CD4+ T cell counts, but have on-going viral replication. We hypothesized that different immunological mechanisms are responsible for preserved CD4+ T cell counts in controllers and LTNP.

U2 - 10.1371/journal.pone.0063744

DO - 10.1371/journal.pone.0063744

M3 - Journal article

VL - 8

SP - e63744

JO - P L o S One

JF - P L o S One

SN - 1932-6203

IS - 5

ER -