Diabetes-related symptom distress in association with glucose metabolism and comorbidity

the Hoorn Study

Marcel C Adriaanse, Frans Pouwer, Jacqueline M Dekker, Giel Nijpels, Coen DA Stehouwer, Robert J Heine, Frank J Snoek

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

OBJECTIVE: The purpose of this study was to determine the associations between diabetes-related symptom distress, glucose metabolism status, and comorbidities of type 2 diabetes.

RESEARCH DESIGN AND METHODS: This was a cross-sectional sample of 281 individuals with normal glucose metabolism (NGM), 181 individuals with impaired glucose metabolism (IGM), and 107 subjects with type 2 diabetes. We used the revised type 2 Diabetes Symptom Checklist (DSC-R) to assess diabetes-related symptom distress.

RESULTS: The total symptom distress score (range 0-100) was relatively low for diabetic subjects (mean +/- SD 8.4 +/- 9.4), although it was significantly different from that for subjects with IGM (6.5 +/- 7.1) and NGM (6.1 +/- 7.9) (F = 3.1, 2 d.f., P = 0.046). Ischemic heart disease was associated with elevated DSC-R scores on three subscales, whereas depression showed higher symptom distress levels across all DSC-R domains.

CONCLUSIONS: Worsening glucose metabolism is associated with increasing diabetes-related symptom distress. This relationship is attenuated by ischemic heart disease and particularly by depression.

OriginalsprogEngelsk
TidsskriftDiabetes Care
Vol/bind31
Udgave nummer12
Sider (fra-til)2268-70
Antal sider3
ISSN0149-5992
DOI
StatusUdgivet - dec. 2008

Fingeraftryk

Comorbidity
Type 2 Diabetes Mellitus
Checklist

Citer dette

Adriaanse, M. C., Pouwer, F., Dekker, J. M., Nijpels, G., Stehouwer, C. DA., Heine, R. J., & Snoek, F. J. (2008). Diabetes-related symptom distress in association with glucose metabolism and comorbidity: the Hoorn Study. Diabetes Care, 31(12), 2268-70. https://doi.org/10.2337/dc08-1074
Adriaanse, Marcel C ; Pouwer, Frans ; Dekker, Jacqueline M ; Nijpels, Giel ; Stehouwer, Coen DA ; Heine, Robert J ; Snoek, Frank J. / Diabetes-related symptom distress in association with glucose metabolism and comorbidity : the Hoorn Study. I: Diabetes Care. 2008 ; Bind 31, Nr. 12. s. 2268-70.
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abstract = "OBJECTIVE: The purpose of this study was to determine the associations between diabetes-related symptom distress, glucose metabolism status, and comorbidities of type 2 diabetes.RESEARCH DESIGN AND METHODS: This was a cross-sectional sample of 281 individuals with normal glucose metabolism (NGM), 181 individuals with impaired glucose metabolism (IGM), and 107 subjects with type 2 diabetes. We used the revised type 2 Diabetes Symptom Checklist (DSC-R) to assess diabetes-related symptom distress.RESULTS: The total symptom distress score (range 0-100) was relatively low for diabetic subjects (mean +/- SD 8.4 +/- 9.4), although it was significantly different from that for subjects with IGM (6.5 +/- 7.1) and NGM (6.1 +/- 7.9) (F = 3.1, 2 d.f., P = 0.046). Ischemic heart disease was associated with elevated DSC-R scores on three subscales, whereas depression showed higher symptom distress levels across all DSC-R domains.CONCLUSIONS: Worsening glucose metabolism is associated with increasing diabetes-related symptom distress. This relationship is attenuated by ischemic heart disease and particularly by depression.",
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Adriaanse, MC, Pouwer, F, Dekker, JM, Nijpels, G, Stehouwer, CDA, Heine, RJ & Snoek, FJ 2008, 'Diabetes-related symptom distress in association with glucose metabolism and comorbidity: the Hoorn Study', Diabetes Care, bind 31, nr. 12, s. 2268-70. https://doi.org/10.2337/dc08-1074

Diabetes-related symptom distress in association with glucose metabolism and comorbidity : the Hoorn Study. / Adriaanse, Marcel C; Pouwer, Frans; Dekker, Jacqueline M; Nijpels, Giel; Stehouwer, Coen DA; Heine, Robert J; Snoek, Frank J.

I: Diabetes Care, Bind 31, Nr. 12, 12.2008, s. 2268-70.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Diabetes-related symptom distress in association with glucose metabolism and comorbidity

T2 - the Hoorn Study

AU - Adriaanse, Marcel C

AU - Pouwer, Frans

AU - Dekker, Jacqueline M

AU - Nijpels, Giel

AU - Stehouwer, Coen DA

AU - Heine, Robert J

AU - Snoek, Frank J

PY - 2008/12

Y1 - 2008/12

N2 - OBJECTIVE: The purpose of this study was to determine the associations between diabetes-related symptom distress, glucose metabolism status, and comorbidities of type 2 diabetes.RESEARCH DESIGN AND METHODS: This was a cross-sectional sample of 281 individuals with normal glucose metabolism (NGM), 181 individuals with impaired glucose metabolism (IGM), and 107 subjects with type 2 diabetes. We used the revised type 2 Diabetes Symptom Checklist (DSC-R) to assess diabetes-related symptom distress.RESULTS: The total symptom distress score (range 0-100) was relatively low for diabetic subjects (mean +/- SD 8.4 +/- 9.4), although it was significantly different from that for subjects with IGM (6.5 +/- 7.1) and NGM (6.1 +/- 7.9) (F = 3.1, 2 d.f., P = 0.046). Ischemic heart disease was associated with elevated DSC-R scores on three subscales, whereas depression showed higher symptom distress levels across all DSC-R domains.CONCLUSIONS: Worsening glucose metabolism is associated with increasing diabetes-related symptom distress. This relationship is attenuated by ischemic heart disease and particularly by depression.

AB - OBJECTIVE: The purpose of this study was to determine the associations between diabetes-related symptom distress, glucose metabolism status, and comorbidities of type 2 diabetes.RESEARCH DESIGN AND METHODS: This was a cross-sectional sample of 281 individuals with normal glucose metabolism (NGM), 181 individuals with impaired glucose metabolism (IGM), and 107 subjects with type 2 diabetes. We used the revised type 2 Diabetes Symptom Checklist (DSC-R) to assess diabetes-related symptom distress.RESULTS: The total symptom distress score (range 0-100) was relatively low for diabetic subjects (mean +/- SD 8.4 +/- 9.4), although it was significantly different from that for subjects with IGM (6.5 +/- 7.1) and NGM (6.1 +/- 7.9) (F = 3.1, 2 d.f., P = 0.046). Ischemic heart disease was associated with elevated DSC-R scores on three subscales, whereas depression showed higher symptom distress levels across all DSC-R domains.CONCLUSIONS: Worsening glucose metabolism is associated with increasing diabetes-related symptom distress. This relationship is attenuated by ischemic heart disease and particularly by depression.

KW - Aged

KW - Analysis of Variance

KW - Comorbidity

KW - Cross-Sectional Studies

KW - Depressive Disorder

KW - Diabetes Mellitus, Type 2

KW - Female

KW - Glucose

KW - Glucose Intolerance

KW - Humans

KW - Male

KW - Middle Aged

KW - Myocardial Ischemia

KW - Journal Article

U2 - 10.2337/dc08-1074

DO - 10.2337/dc08-1074

M3 - Journal article

VL - 31

SP - 2268

EP - 2270

JO - Diabetes Care

JF - Diabetes Care

SN - 0149-5992

IS - 12

ER -