Detrusor instability in children with recurrent urinary tract infection and/or enuresis. II. Treatment

N Qvist, K K Nielsen, E S Kristensen, D Ehlers, K M Jensen, T Krarup, J Christoffersen

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review


Of 41 children, aged 5-15 years, referred consecutively because of recurrent urinary tract infections (UTIs) and/or enuresis, 18 (44%) showed detrusor instability (DI) in at least 2 of 6 CO2 cystometries. One child was excluded from the study because of lack of follow-up. Four children with less pronounced DI (instability during less than or equal to 50% of the cystometries performed) and frequent UTIs were given antibiotics prophylactically for 3 months. In the remaining 13 children, DI was found during more than half the cystometries performed, and 11 of these children, who also had urge incontinence, were treated with emepronium bromide, 400-600 mg daily (10-12 mg/kg) for 3 months. In 7 of the patients this treatment was supplemented by antibiotics prophylactically because of frequent UTIs. Two children with special problems received other types of treatment. All children were free from symptoms at a clinical check-up 6 months later, 95% confidence limits 0-20%.
TidsskriftUrologia Internationalis
Udgave nummer3
Sider (fra-til)199-201
Antal sider3
StatusUdgivet - 1986


  • Adolescent
  • Anti-Bacterial Agents
  • Child
  • Child, Preschool
  • Cystoscopy
  • Emepronium
  • Enuresis
  • Female
  • Humans
  • Male
  • Muscle, Smooth
  • Urinary Bladder
  • Urinary Bladder Diseases
  • Urinary Tract Infections
  • Urodynamics


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