Danske anbefalinger for behandling af ankyloserende spondylitis og spondylartritis udarbejdet i et internationalt projektsamarbejde

Susanne Juhl Pedersen, Ole Rintek Madsen, Jon Erlendsson, Berit Schiøttz-Christensen, Inge Juul Sørensen, Lis Smedegaard Andersen, Mikkel Ostergaard

Publikation: Bidrag til tidsskriftTidsskriftartikelFormidling


INTRODUCTION: The multinational initiative "3e Initiative in Rheumatology - Multi-national Recommendations for the Management of Ankylosing Spondylitis 2006-7" served the primary purpose of providing specific recommendations for the management of ankylosing spondylitis and spondyloarthritis patients in daily practice. MATERIAL AND METHODs: The scientific committees from the ten participating countries selected nine clinical questions regarding diagnosis, monitoring and pharmacologic non-biologic treatment, and the Danish group chose 2 additional questions about non-pharmacologic treatment. Systematic literature searches were performed in Medline by 3 international and a Danish bibliographic fellow. Outcome data were extracted and processed by use of routine methods from clinical epidemiology and statistics. The evidence was presented to the Danish rheumatologists. The participants were divided into three groups, which each proposed recommendations. After a final plenary discussion, a voting session took place. Subsequently, agreement was obtained, and the strength of the recommendations was graded.

RESULTS: The bibliographic fellows identified 2,709 relevant manuscripts and included 477 of these in the analysis. All 186 Danish rheumatologists were invited, and 26 (14,0%) participated in the meeting held in Copenhagen, December 2006. The individual recommendations were endorsed by 68-100% of the participants.

CONCLUSION: Within the framework of the multinational 3e project, it was possible to develop Danish recommendations for AS patients by combining an evidence-based approach and the experience of clinical rheumatologists.

TidsskriftUgeskrift for Laeger
Udgave nummer49
Sider (fra-til)4044-50
Antal sider7
StatusUdgivet - 1. dec. 2008



  • Denmark
  • Evidence-Based Medicine
  • Exercise Therapy
  • Humans
  • International Cooperation
  • Outcome and Process Assessment (Health Care)
  • Practice Guidelines as Topic
  • Spondylarthritis
  • Spondylitis, Ankylosing


Pedersen, S. J., Madsen, O. R., Erlendsson, J., Schiøttz-Christensen, B., Sørensen, I. J., Andersen, L. S., & Ostergaard, M. (2008). Danske anbefalinger for behandling af ankyloserende spondylitis og spondylartritis udarbejdet i et internationalt projektsamarbejde. Ugeskrift for Laeger, 170(49), 4044-50.