D-2-Hydroxyglutarate Is an Intercellular Mediator in IDH-Mutant Gliomas Inhibiting Complement and T Cells

Immunology and Microbiology

• T Cell 100%
• Mediator 100%
• Immunity 66%
• CD4 66%
• Complement Activation 66%
• FOXP3 66%
• Phagocytosis 33%
• Cell Function 33%
• Cell Differentiation 33%
• Tumor Cell 33%
• Dendritic Cell 33%
• Immune System 33%
• Cytotoxic T-Cell 33%
• T-Helper Cell 33%
• Cell Damage 33%
• CD8 33%
• Cell Migration 33%
• Opsonization 33%
• Cytokine Release 33%
• Somatic Mutation 33%
• IC3b 33%
• Gain of Function Mutation 33%
• C3b 33%
• Cell Infiltration 33%
• Immune Escape 33%
• Glioma Cell 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Isocitrate Dehydrogenase 100%
• Neoplasm 40%
• CD8 Antigen 40%
• Cytokine 20%
• Primary Tumor 20%
• Tumor Growth 20%
• Complement Component C3b 20%
• Tumor Microenvironment 20%
• Isocitrate Dehydrogenase 1 20%