Cytogenetic studies of 11 meningiomas and their clinical significance. II

L Poulsgård, H D Schrøder, M Rønne

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Cytogenetic analyses of 11 consecutive cases of meningiomas from 7 female and 4 male patients are reported. Chromosomal abnormalities were found in all cases. Only two of the cases showed cells with normal karyotype in addition to the abnormal stemline. Two of the cases displayed a more aggressive growth pattern than is usually seen in meningiomas. The first case was characterized by tumor invasion into the bone, a stemline with monosomy 22 and a hyperhaploid sideline. The second case was characterized by recurrency and a hypodiploid stemline. Extended clonal evolution was observed in one case.

OriginalsprogEngelsk
TidsskriftAnticancer Research
Vol/bind10
Udgave nummer2B
Sider (fra-til)535-8
Antal sider4
ISSN0250-7005
StatusUdgivet - 1. mar. 1990

Fingeraftryk

Meningioma
Cytogenetics
Clonal Evolution
Growth
Neoplasms

Citer dette

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abstract = "Cytogenetic analyses of 11 consecutive cases of meningiomas from 7 female and 4 male patients are reported. Chromosomal abnormalities were found in all cases. Only two of the cases showed cells with normal karyotype in addition to the abnormal stemline. Two of the cases displayed a more aggressive growth pattern than is usually seen in meningiomas. The first case was characterized by tumor invasion into the bone, a stemline with monosomy 22 and a hyperhaploid sideline. The second case was characterized by recurrency and a hypodiploid stemline. Extended clonal evolution was observed in one case.",
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Cytogenetic studies of 11 meningiomas and their clinical significance. II. / Poulsgård, L; Schrøder, H D; Rønne, M.

I: Anticancer Research, Bind 10, Nr. 2B, 01.03.1990, s. 535-8.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Cytogenetic studies of 11 meningiomas and their clinical significance. II

AU - Poulsgård, L

AU - Schrøder, H D

AU - Rønne, M

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N2 - Cytogenetic analyses of 11 consecutive cases of meningiomas from 7 female and 4 male patients are reported. Chromosomal abnormalities were found in all cases. Only two of the cases showed cells with normal karyotype in addition to the abnormal stemline. Two of the cases displayed a more aggressive growth pattern than is usually seen in meningiomas. The first case was characterized by tumor invasion into the bone, a stemline with monosomy 22 and a hyperhaploid sideline. The second case was characterized by recurrency and a hypodiploid stemline. Extended clonal evolution was observed in one case.

AB - Cytogenetic analyses of 11 consecutive cases of meningiomas from 7 female and 4 male patients are reported. Chromosomal abnormalities were found in all cases. Only two of the cases showed cells with normal karyotype in addition to the abnormal stemline. Two of the cases displayed a more aggressive growth pattern than is usually seen in meningiomas. The first case was characterized by tumor invasion into the bone, a stemline with monosomy 22 and a hyperhaploid sideline. The second case was characterized by recurrency and a hypodiploid stemline. Extended clonal evolution was observed in one case.

KW - Adult

KW - Aged

KW - Chromosome Aberrations

KW - Female

KW - Humans

KW - Male

KW - Meningeal Neoplasms

KW - Meningioma

KW - Middle Aged

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

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