Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation

Jiusong Sun, Jie Zhang, Jes Sanddal Lindholt, Galina K Sukhova, Jian Liu, Aina He, Magnus Åbrink, Gunnar Pejler, Richard Lee Stevens, Robert W. Thompson, Terri L Ennis, Michael F Gurish, Peter Libby, Guo-Ping Shi

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Mast cell chymase may participate in the pathogenesis of human abdominal aortic aneurysm (AAA), yet a direct contribution of this serine protease to AAA formation remains unknown.
OriginalsprogEngelsk
TidsskriftCirculation
Vol/bind120
Udgave nummer11
Sider (fra-til)973-982
ISSN0009-7322
DOI
StatusUdgivet - 2009

Fingeraftryk

Abdominal Aortic Aneurysm
Mast Cells

Citer dette

Sun, Jiusong ; Zhang, Jie ; Lindholt, Jes Sanddal ; Sukhova, Galina K ; Liu, Jian ; He, Aina ; Åbrink, Magnus ; Pejler, Gunnar ; Stevens, Richard Lee ; Thompson, Robert W. ; Ennis, Terri L ; Gurish, Michael F ; Libby, Peter ; Shi, Guo-Ping. / Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation. I: Circulation. 2009 ; Bind 120, Nr. 11. s. 973-982.
@article{0254513d774e4ec48d6b8f50140ff4b5,
title = "Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation",
abstract = "Mast cell chymase may participate in the pathogenesis of human abdominal aortic aneurysm (AAA), yet a direct contribution of this serine protease to AAA formation remains unknown.",
keywords = "Adult, Aged, Aged, 80 and over, Animals, Aortic Aneurysm, Abdominal, Apoptosis, Cathepsins, Chymases, Disease Models, Animal, Female, Gene Expression Regulation, Enzymologic, Humans, Macrophages, Male, Mast Cells, Mice, Mice, Inbred C57BL, Mice, Mutant Strains, Microcirculation, Middle Aged, Muscle, Smooth, Vascular, Serine Endopeptidases",
author = "Jiusong Sun and Jie Zhang and Lindholt, {Jes Sanddal} and Sukhova, {Galina K} and Jian Liu and Aina He and Magnus {\AA}brink and Gunnar Pejler and Stevens, {Richard Lee} and Thompson, {Robert W.} and Ennis, {Terri L} and Gurish, {Michael F} and Peter Libby and Guo-Ping Shi",
year = "2009",
doi = "10.1161/CIRCULATIONAHA.109.849679",
language = "English",
volume = "120",
pages = "973--982",
journal = "Circulation",
issn = "0009-7322",
publisher = "Lippincott Williams & Wilkins",
number = "11",

}

Sun, J, Zhang, J, Lindholt, JS, Sukhova, GK, Liu, J, He, A, Åbrink, M, Pejler, G, Stevens, RL, Thompson, RW, Ennis, TL, Gurish, MF, Libby, P & Shi, G-P 2009, 'Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation', Circulation, bind 120, nr. 11, s. 973-982. https://doi.org/10.1161/CIRCULATIONAHA.109.849679

Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation. / Sun, Jiusong; Zhang, Jie; Lindholt, Jes Sanddal; Sukhova, Galina K; Liu, Jian; He, Aina; Åbrink, Magnus; Pejler, Gunnar; Stevens, Richard Lee; Thompson, Robert W.; Ennis, Terri L; Gurish, Michael F; Libby, Peter; Shi, Guo-Ping.

I: Circulation, Bind 120, Nr. 11, 2009, s. 973-982.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation

AU - Sun, Jiusong

AU - Zhang, Jie

AU - Lindholt, Jes Sanddal

AU - Sukhova, Galina K

AU - Liu, Jian

AU - He, Aina

AU - Åbrink, Magnus

AU - Pejler, Gunnar

AU - Stevens, Richard Lee

AU - Thompson, Robert W.

AU - Ennis, Terri L

AU - Gurish, Michael F

AU - Libby, Peter

AU - Shi, Guo-Ping

PY - 2009

Y1 - 2009

N2 - Mast cell chymase may participate in the pathogenesis of human abdominal aortic aneurysm (AAA), yet a direct contribution of this serine protease to AAA formation remains unknown.

AB - Mast cell chymase may participate in the pathogenesis of human abdominal aortic aneurysm (AAA), yet a direct contribution of this serine protease to AAA formation remains unknown.

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Animals

KW - Aortic Aneurysm, Abdominal

KW - Apoptosis

KW - Cathepsins

KW - Chymases

KW - Disease Models, Animal

KW - Female

KW - Gene Expression Regulation, Enzymologic

KW - Humans

KW - Macrophages

KW - Male

KW - Mast Cells

KW - Mice

KW - Mice, Inbred C57BL

KW - Mice, Mutant Strains

KW - Microcirculation

KW - Middle Aged

KW - Muscle, Smooth, Vascular

KW - Serine Endopeptidases

U2 - 10.1161/CIRCULATIONAHA.109.849679

DO - 10.1161/CIRCULATIONAHA.109.849679

M3 - Journal article

VL - 120

SP - 973

EP - 982

JO - Circulation

JF - Circulation

SN - 0009-7322

IS - 11

ER -