Copper bis-Dipyridoquinoxaline Is a Potent DNA Intercalator that Induces Superoxide-Mediated Cleavage via the Minor Groove

Fysik og astronomi

• inorganic peroxides 90%
• cleavage 64%
• grooves 62%
• deoxyribonucleic acid 57%
• copper 44%
• nuclease 39%
• affinity 27%
• quinoxalines 20%
• damage 17%
• guanines 17%
• hydroxyl radicals 16%
• oligomers 14%
• reagents 14%
• crystallography 14%
• cations 10%
• oxidation 9%
• viscosity 9%
• synthesis 9%
• characterization 6%
• profiles 6%
• x rays 5%

Medicin og biovidenskab

• Intercalating Agents 100%
• Superoxides 63%
• Copper 63%
• Reducing Agents 39%
• DNA 35%
• 1,10-phenanthroline 23%
• Quinoxalines 23%
• 5-Methylcytosine 22%
• X Ray Crystallography 21%
• Cytosine 18%
• Guanine 18%
• Hydroxyl Radical 17%
• Viscosity 17%
• Oxidants 16%
• Cations 15%
• DNA Damage 13%

Kemiske forbindelser

• 5-Methylcytosine 45%
• Cleavage 43%
• Quinoxaline 35%
• 1,10-phenanthroline 30%
• Binding Agent 27%
• X-Ray Crystallography 26%
• Oligomer 25%
• Kd 23%
• Block Like Crystal 21%
• Cation 18%
• Oxidation Reaction 14%