COPD: Definition and Phenotypes

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Chronic obstructive pulmonary disease (COPD) is currently defined as a common preventable and treatable disease that is characterized by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases. Exacerbations and comorbidities contribute to the overall severity in individual patients. The evolution of this definition and the diagnostic criteria currently in use are discussed. COPD is increasingly divided in subgroups or phenotypes based on specific features and association with prognosis or response to therapy, the most notable being the feature of frequent exacerbations.
OriginalsprogEngelsk
TidsskriftClinics in Chest Medicine
Vol/bind35
Udgave nummer1
Sider (fra-til)1-6
ISSN0272-5231
DOI
StatusUdgivet - 2014

Bibliografisk note

ISI Document Delivery No.: AB8NR Times Cited: 2 Cited Reference Count: 24 Vestbo, Jorgen 2 W B SAUNDERS CO-ELSEVIER INC PHILADELPHIA CLIN CHEST MED

Citer dette

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title = "COPD: Definition and Phenotypes",
abstract = "Chronic obstructive pulmonary disease (COPD) is currently defined as a common preventable and treatable disease that is characterized by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases. Exacerbations and comorbidities contribute to the overall severity in individual patients. The evolution of this definition and the diagnostic criteria currently in use are discussed. COPD is increasingly divided in subgroups or phenotypes based on specific features and association with prognosis or response to therapy, the most notable being the feature of frequent exacerbations.",
keywords = "COPD Definition Diagnosis Lung function Chronic inflammation OBSTRUCTIVE PULMONARY-DISEASE DIAGNOSIS MANAGEMENT",
author = "J. Vestbo",
note = "ISI Document Delivery No.: AB8NR Times Cited: 2 Cited Reference Count: 24 Vestbo, Jorgen 2 W B SAUNDERS CO-ELSEVIER INC PHILADELPHIA CLIN CHEST MED",
year = "2014",
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COPD: Definition and Phenotypes. / Vestbo, J.

I: Clinics in Chest Medicine, Bind 35, Nr. 1, 2014, s. 1-6.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - COPD: Definition and Phenotypes

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N2 - Chronic obstructive pulmonary disease (COPD) is currently defined as a common preventable and treatable disease that is characterized by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases. Exacerbations and comorbidities contribute to the overall severity in individual patients. The evolution of this definition and the diagnostic criteria currently in use are discussed. COPD is increasingly divided in subgroups or phenotypes based on specific features and association with prognosis or response to therapy, the most notable being the feature of frequent exacerbations.

AB - Chronic obstructive pulmonary disease (COPD) is currently defined as a common preventable and treatable disease that is characterized by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases. Exacerbations and comorbidities contribute to the overall severity in individual patients. The evolution of this definition and the diagnostic criteria currently in use are discussed. COPD is increasingly divided in subgroups or phenotypes based on specific features and association with prognosis or response to therapy, the most notable being the feature of frequent exacerbations.

KW - COPD Definition Diagnosis Lung function Chronic inflammation OBSTRUCTIVE PULMONARY-DISEASE DIAGNOSIS MANAGEMENT

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DO - 10.1016/j.ccm.2013.10.010

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