Resumé
We compared wound infiltration with small-dose tenoxicam (7.5 mg) to intramuscular (IM) administration of the same dose to treat pain after herniorrhaphy. In a randomized, double-blind study, 50 patients received either preoperative wound infiltration with tenoxicam, 7.5 mg in 40 mL of 0.9% saline (WI group; n = 25) or IM tenoxicam 7.5 mg (IM group; n = 25). In each group a saline placebo of equal volume was given by the alternate route, i.e., those who received wound infiltration with tenoxicam received 0.75 mL of 0.9% saline IM; those who received IM tenoxicam received 40 mL of 0.9% saline for wound infiltration. Postoperative pain was assessed with a verbal pain scale and a visual analog scale (VAS) at rest and during movement and cough, 1, 2, 4, 6, and 24 h postoperatively. Wound tenderness was assessed with an electronic algometer preoperatively, and 2, 4, and 6 h postoperatively. The need for supplementary analgesics (acetaminophen and morphine) was registered. No differences were observed between groups in VAS pain scores, verbal rating pain scores, pain pressure thresholds, or in need for supplementary analgesics. We conclude that tenoxicam 7.5 mg has no local analgesic effect on postoperative pain after herniorrhaphy.
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | Anesthesia and Analgesia |
| Vol/bind | 83 |
| Udgave nummer | 6 |
| Sider (fra-til) | 1239-43 |
| Antal sider | 5 |
| ISSN | 0003-2999 |
| Status | Udgivet - dec. 1996 |
| Udgivet eksternt | Ja |
Fingeraftryk
Citer dette
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Comparison of tenoxicam by intramuscular injection or wound infiltration for analgesia after inguinal herniorrhaphy. / Mikkelsen, S S; Knudsen, K E; Kristensen, B B; Linnemann, M U; Friis, E; Dahl, J B.
I: Anesthesia and Analgesia, Bind 83, Nr. 6, 12.1996, s. 1239-43.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
TY - JOUR
T1 - Comparison of tenoxicam by intramuscular injection or wound infiltration for analgesia after inguinal herniorrhaphy
AU - Mikkelsen, S S
AU - Knudsen, K E
AU - Kristensen, B B
AU - Linnemann, M U
AU - Friis, E
AU - Dahl, J B
PY - 1996/12
Y1 - 1996/12
N2 - We compared wound infiltration with small-dose tenoxicam (7.5 mg) to intramuscular (IM) administration of the same dose to treat pain after herniorrhaphy. In a randomized, double-blind study, 50 patients received either preoperative wound infiltration with tenoxicam, 7.5 mg in 40 mL of 0.9% saline (WI group; n = 25) or IM tenoxicam 7.5 mg (IM group; n = 25). In each group a saline placebo of equal volume was given by the alternate route, i.e., those who received wound infiltration with tenoxicam received 0.75 mL of 0.9% saline IM; those who received IM tenoxicam received 40 mL of 0.9% saline for wound infiltration. Postoperative pain was assessed with a verbal pain scale and a visual analog scale (VAS) at rest and during movement and cough, 1, 2, 4, 6, and 24 h postoperatively. Wound tenderness was assessed with an electronic algometer preoperatively, and 2, 4, and 6 h postoperatively. The need for supplementary analgesics (acetaminophen and morphine) was registered. No differences were observed between groups in VAS pain scores, verbal rating pain scores, pain pressure thresholds, or in need for supplementary analgesics. We conclude that tenoxicam 7.5 mg has no local analgesic effect on postoperative pain after herniorrhaphy.
AB - We compared wound infiltration with small-dose tenoxicam (7.5 mg) to intramuscular (IM) administration of the same dose to treat pain after herniorrhaphy. In a randomized, double-blind study, 50 patients received either preoperative wound infiltration with tenoxicam, 7.5 mg in 40 mL of 0.9% saline (WI group; n = 25) or IM tenoxicam 7.5 mg (IM group; n = 25). In each group a saline placebo of equal volume was given by the alternate route, i.e., those who received wound infiltration with tenoxicam received 0.75 mL of 0.9% saline IM; those who received IM tenoxicam received 40 mL of 0.9% saline for wound infiltration. Postoperative pain was assessed with a verbal pain scale and a visual analog scale (VAS) at rest and during movement and cough, 1, 2, 4, 6, and 24 h postoperatively. Wound tenderness was assessed with an electronic algometer preoperatively, and 2, 4, and 6 h postoperatively. The need for supplementary analgesics (acetaminophen and morphine) was registered. No differences were observed between groups in VAS pain scores, verbal rating pain scores, pain pressure thresholds, or in need for supplementary analgesics. We conclude that tenoxicam 7.5 mg has no local analgesic effect on postoperative pain after herniorrhaphy.
KW - Abdomen/surgery
KW - Acetaminophen/administration & dosage
KW - Adult
KW - Aged
KW - Aged, 80 and over
KW - Analgesia/methods
KW - Analgesics, Non-Narcotic/administration & dosage
KW - Analgesics, Opioid/administration & dosage
KW - Anti-Inflammatory Agents, Non-Steroidal/administration & dosage
KW - Double-Blind Method
KW - Female
KW - Hernia, Inguinal/surgery
KW - Humans
KW - Injections, Intradermal
KW - Injections, Intramuscular
KW - Male
KW - Middle Aged
KW - Morphine/administration & dosage
KW - Movement
KW - Pain Measurement
KW - Pain Threshold/drug effects
KW - Pain, Postoperative/drug therapy
KW - Piroxicam/administration & dosage
KW - Placebos
KW - Rest
M3 - Journal article
VL - 83
SP - 1239
EP - 1243
JO - Anesthesia and Analgesia
JF - Anesthesia and Analgesia
SN - 0003-2999
IS - 6
ER -