Comparison of permethrin 2.5 % cream vs. Tenutex emulsion for the treatment of scabies.

Mohamad Goldust*, Elham Rezaee, Ramin Raghifar, Mohammad Naghavi-Behzad

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Resumé

Scabies is a common parasitic infestation that is an important public-health problem in many resource-poor regions. It is commonly treated with the insecticides but the treatment of choice is still controversial. This study aimed at comparing the efficacy of permethrin 2.5% cream vs. Tenutex emulsion for the treatment of scabies. In total, 440 patients with scabies were enrolled, and randomized into two groups The first group received permethrin 2.5% cream twice with one week interval and the second group received Tenutex emulsion and were told to apply this once whole-body application. Treatment was evaluated at intervals of 2 and 4 weeks, and if there was treatment failure at the 2-week follow-up, treatment was repeated.Two application of permethrin 2.5% cream provided a cure rate of 63.6% at the 2-week follow-up, which increased to 86.3% at the 4-week follow-up after repeating the treatment. Treatment with single applications of Tenutex emulsion was effective in 45.4% of patients at the 2-week follow-up, which increased to 59.1% at the 4-week follow-up after this treatment was repeated.Two application of permethrin 2.5% cream was as effective as single applications of Tenutex emulsion at the 2-week follow-up. After repeating the treatment, permethrin 2.5% cream was superior to Tenutex emulsion at the 4-week follow up.

OriginalsprogEngelsk
TidsskriftAnnals of Parasitology
Vol/bind59
Udgave nummer1
Sider (fra-til)31-35
Antal sider5
ISSN2299-0631
StatusUdgivet - 1. jan. 2013

Fingeraftryk

Permethrin
Scabies
Insecticides
Treatment Failure
Public Health

Citer dette

Goldust, Mohamad ; Rezaee, Elham ; Raghifar, Ramin ; Naghavi-Behzad, Mohammad. / Comparison of permethrin 2.5 % cream vs. Tenutex emulsion for the treatment of scabies. I: Annals of Parasitology. 2013 ; Bind 59, Nr. 1. s. 31-35.
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title = "Comparison of permethrin 2.5 {\%} cream vs. Tenutex emulsion for the treatment of scabies.",
abstract = "Scabies is a common parasitic infestation that is an important public-health problem in many resource-poor regions. It is commonly treated with the insecticides but the treatment of choice is still controversial. This study aimed at comparing the efficacy of permethrin 2.5{\%} cream vs. Tenutex emulsion for the treatment of scabies. In total, 440 patients with scabies were enrolled, and randomized into two groups The first group received permethrin 2.5{\%} cream twice with one week interval and the second group received Tenutex emulsion and were told to apply this once whole-body application. Treatment was evaluated at intervals of 2 and 4 weeks, and if there was treatment failure at the 2-week follow-up, treatment was repeated.Two application of permethrin 2.5{\%} cream provided a cure rate of 63.6{\%} at the 2-week follow-up, which increased to 86.3{\%} at the 4-week follow-up after repeating the treatment. Treatment with single applications of Tenutex emulsion was effective in 45.4{\%} of patients at the 2-week follow-up, which increased to 59.1{\%} at the 4-week follow-up after this treatment was repeated.Two application of permethrin 2.5{\%} cream was as effective as single applications of Tenutex emulsion at the 2-week follow-up. After repeating the treatment, permethrin 2.5{\%} cream was superior to Tenutex emulsion at the 4-week follow up.",
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Comparison of permethrin 2.5 % cream vs. Tenutex emulsion for the treatment of scabies. / Goldust, Mohamad; Rezaee, Elham; Raghifar, Ramin; Naghavi-Behzad, Mohammad.

I: Annals of Parasitology, Bind 59, Nr. 1, 01.01.2013, s. 31-35.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Comparison of permethrin 2.5 % cream vs. Tenutex emulsion for the treatment of scabies.

AU - Goldust, Mohamad

AU - Rezaee, Elham

AU - Raghifar, Ramin

AU - Naghavi-Behzad, Mohammad

PY - 2013/1/1

Y1 - 2013/1/1

N2 - Scabies is a common parasitic infestation that is an important public-health problem in many resource-poor regions. It is commonly treated with the insecticides but the treatment of choice is still controversial. This study aimed at comparing the efficacy of permethrin 2.5% cream vs. Tenutex emulsion for the treatment of scabies. In total, 440 patients with scabies were enrolled, and randomized into two groups The first group received permethrin 2.5% cream twice with one week interval and the second group received Tenutex emulsion and were told to apply this once whole-body application. Treatment was evaluated at intervals of 2 and 4 weeks, and if there was treatment failure at the 2-week follow-up, treatment was repeated.Two application of permethrin 2.5% cream provided a cure rate of 63.6% at the 2-week follow-up, which increased to 86.3% at the 4-week follow-up after repeating the treatment. Treatment with single applications of Tenutex emulsion was effective in 45.4% of patients at the 2-week follow-up, which increased to 59.1% at the 4-week follow-up after this treatment was repeated.Two application of permethrin 2.5% cream was as effective as single applications of Tenutex emulsion at the 2-week follow-up. After repeating the treatment, permethrin 2.5% cream was superior to Tenutex emulsion at the 4-week follow up.

AB - Scabies is a common parasitic infestation that is an important public-health problem in many resource-poor regions. It is commonly treated with the insecticides but the treatment of choice is still controversial. This study aimed at comparing the efficacy of permethrin 2.5% cream vs. Tenutex emulsion for the treatment of scabies. In total, 440 patients with scabies were enrolled, and randomized into two groups The first group received permethrin 2.5% cream twice with one week interval and the second group received Tenutex emulsion and were told to apply this once whole-body application. Treatment was evaluated at intervals of 2 and 4 weeks, and if there was treatment failure at the 2-week follow-up, treatment was repeated.Two application of permethrin 2.5% cream provided a cure rate of 63.6% at the 2-week follow-up, which increased to 86.3% at the 4-week follow-up after repeating the treatment. Treatment with single applications of Tenutex emulsion was effective in 45.4% of patients at the 2-week follow-up, which increased to 59.1% at the 4-week follow-up after this treatment was repeated.Two application of permethrin 2.5% cream was as effective as single applications of Tenutex emulsion at the 2-week follow-up. After repeating the treatment, permethrin 2.5% cream was superior to Tenutex emulsion at the 4-week follow up.

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