Cohort profile: Copenhagen Hospital Biobank-chronic inflammatory disease-inflammatory bowel disease (CHB-CID:IBD) genetic cohort

  • Malene Rohr Andersen
  • , Maria Didriksen
  • , Maria Joanna Alexandraki
  • , Marianne Kragh Thomsen
  • , Mette Julsgaard
  • , Mette Nyegaard
  • , Michael Schwinn
  • , Mikael Njai Leite
  • , Natalia Pedersen
  • , Ole Kristian Bonderup
  • , Palle Duun Rohde
  • , Pernille Dige Ovesen
  • , Sanaz Saboori
  • , Sofie Holm-Christensen
  • , Susan Mikkelsen
  • , Thomas Werge
  • , Johan Burisch
  • , Merete Lund Hetland
  • , Bente Glintborg
  • , Christian Erikstrup
  • Søren Brunak, Henrik Ullum, Sisse Rye Ostrowski, Cohort profile: Copenhagen Hospital Biobank-chronic inflammatory disease-inflammatory bowel disease (CHB-CID:IBD) genetic cohort

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstract

The Copenhagen Hospital Biobank-chronic inflammatory disease-inflammatory bowel disease (CHB-CID: IBD) cohort contributes to genetic research in inflammatory bowel disease, including Crohn's disease and ulcerative colitis. Of the 327,084 enrolled and genotyped individuals in the cohort, 10,626 have been diagnosed with IBD as of May 2023. The CHB-CID: IBD cohort includes both patients without IBD and healthy blood donors as control groups. Clinical data is collected from Danish registries and patient records, including details on hospital contacts, co-morbidities, medication, surgical procedures, and laboratory investigations. The cohort features a wide age range (> 18 years), extensive population coverage representative of Danish adults, and validated IBD diagnoses. Finally, the cohort benefits from continuous recruitment and regular updates of clinical information. The aim is to enhance IBD management and ultimately improve patients' quality of life.

OriginalsprogEngelsk
TidsskriftEuropean Journal of Epidemiology
Vol/bind40
Udgave nummer6
Sider (fra-til)721-734
ISSN0393-2990
DOI
StatusUdgivet - jun. 2025

Bibliografisk note

© 2025. The Author(s).

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