TY - JOUR
T1 - Cohort Profile
T2 - Collaboration of Observational HIV Epidemiological Research Europe (COHERE) in EuroCoord
AU - Chêne, Geneviève
AU - Phillips, Andrew
AU - Costagliola, Dominique
AU - Sterne, Jonathan A C
AU - Furrer, Hansjakob
AU - Del Amo, Julia
AU - Mocroft, Amanda
AU - d'Arminio Monforte, Antonella
AU - Dabis, François
AU - Miro, José M
AU - Barger, Diana
AU - Termote, Monique
AU - Schwimmer, Christine
AU - Salbøl Brandt, Rikke
AU - Friis-Moller, Nina
AU - Raben, Dorthe
AU - Haerry, David
AU - Egger, Matthias
AU - Weller, Ian
AU - De Wit, Stephane
PY - 2017/6/1
Y1 - 2017/6/1
N2 - Many questions about the long-term effects of combination antiretroviral therapy (cART) on clinical outcomes in people living with HIV (PLWH) and their impact on health systems remain unanswered. The Collaboration of Observational HIV Epidemiological Research Europe (COHERE) was formed in 2005 to pool and harmonize existing longitudinal data on people living with HIV in Europe, to answer key research questions that could not be addressed adequately by individual cohorts. Key research questions include long-term prognosis, rare outcomes, and variations across patient groups, settings and health systems. COHERE uses the HIV Cohorts Data Exchange Protocol, a standardized and validated method of data structure and transfer, to compile data from over 40 cohorts of PLWH residing in Europe, representing 331 481 individuals, including 2808 children (<13), representing 2 135 896 person-years of follow-up. COHERE compiles data on clinical characteristics, antiretroviral therapy and other medications, HIV seroconversion, opportunistic infections, laboratory results and socio demographic data. External collaborators interested in conducting a project in COHERE should submit a project proposal to the Regional Coordinating Centres in Bordeaux and Copenhagen for review by COHERE’s governing bodies (see www.cohere.org for further information).
AB - Many questions about the long-term effects of combination antiretroviral therapy (cART) on clinical outcomes in people living with HIV (PLWH) and their impact on health systems remain unanswered. The Collaboration of Observational HIV Epidemiological Research Europe (COHERE) was formed in 2005 to pool and harmonize existing longitudinal data on people living with HIV in Europe, to answer key research questions that could not be addressed adequately by individual cohorts. Key research questions include long-term prognosis, rare outcomes, and variations across patient groups, settings and health systems. COHERE uses the HIV Cohorts Data Exchange Protocol, a standardized and validated method of data structure and transfer, to compile data from over 40 cohorts of PLWH residing in Europe, representing 331 481 individuals, including 2808 children (<13), representing 2 135 896 person-years of follow-up. COHERE compiles data on clinical characteristics, antiretroviral therapy and other medications, HIV seroconversion, opportunistic infections, laboratory results and socio demographic data. External collaborators interested in conducting a project in COHERE should submit a project proposal to the Regional Coordinating Centres in Bordeaux and Copenhagen for review by COHERE’s governing bodies (see www.cohere.org for further information).
KW - Adult
KW - Anti-Retroviral Agents/therapeutic use
KW - Antiretroviral Therapy, Highly Active/methods
KW - CD4 Lymphocyte Count
KW - Cohort Studies
KW - Cooperative Behavior
KW - Epidemiologic Studies
KW - Europe/epidemiology
KW - Female
KW - HIV Infections/diagnosis
KW - HIV-1/drug effects
KW - Humans
KW - Male
KW - Treatment Outcome
U2 - 10.1093/ije/dyw211
DO - 10.1093/ije/dyw211
M3 - Journal article
C2 - 27864413
SN - 0300-5771
VL - 46
SP - 797-797n
JO - International Journal of Epidemiology
JF - International Journal of Epidemiology
IS - 3
ER -