Co-circulation of multiple enterovirus D68 subclades, including a novel B3 cluster, across Europe in a season of expected low prevalence, 2019/20

Sofie Elisabeth Midgley, Kimberley Benschop, Robert Dyrdak, Audrey Mirand, Jean-Luc Bailly, Sibylle Bierbaum, Stefan Buderus, Sindy Böttcher, Anna-Maria Eis-Hübinger, Mario Hönemann, Veronika Vorobieva Jensen, Ulla Birgitte Hartling, Cécile Henquell, Marcus Panning, Marianne Kragh Thomsen, Emma B Hodcroft, Adam Meijer

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Abstrakt

Enterovirus D68 (EV-D68) was detected in 93 patients from five European countries between 1 January 2019 and 15 January 2020, a season with expected low circulation. Patients were primarily children (n = 67, median age: 4 years), 59 patients required hospitalisation and five had severe neurologic manifestations. Phylogenetic analysis revealed two clusters in the B3 subclade and subclade A2/D. This circulation of EV-D68 associated with neurological manifestations stresses the importance of surveillance and diagnostics beyond expected peak years.

OriginalsprogEngelsk
Artikelnummer1900749
TidsskriftEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Vol/bind25
Udgave nummer2
Antal sider12
ISSN1025-496X
DOI
StatusUdgivet - 16. jan. 2020
Udgivet eksterntJa

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Citationsformater

Midgley, S. E., Benschop, K., Dyrdak, R., Mirand, A., Bailly, J-L., Bierbaum, S., Buderus, S., Böttcher, S., Eis-Hübinger, A-M., Hönemann, M., Jensen, V. V., Hartling, U. B., Henquell, C., Panning, M., Thomsen, M. K., Hodcroft, E. B., & Meijer, A. (2020). Co-circulation of multiple enterovirus D68 subclades, including a novel B3 cluster, across Europe in a season of expected low prevalence, 2019/20. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 25(2), [1900749]. https://doi.org/10.2807/1560-7917.ES.2020.25.2.1900749