Clonidine sedation effects in children during electroencephalography

Mohammad Barzegar, Reza Piri, Mohammad Naghavi-Behzad, Masoumeh Ghasempour*

*Kontaktforfatter for dette arbejde

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Resumé

It is very important to have proper management in children with Seizure. Electroencephalography (EEG) as a diagnostic instrument has a key role in determining the management method of seizure in children. Because of poor cooperation of some children (especially children with attention deficit hyperactivity disorders and developmental disorders) in performing EEG, it is the best choice to sedate children before EEG. The aim of present study is to evaluate the sedation efficacy of clonidine in children before EEG. In a randomized clinical trial, 45 children age 2 to 12 with seizure, who referred to Children Hospital of Tabriz University of Medical Sciences and candidate for EEG, were studied. Sedation before EEG induced by 0.5 to 2.0 mg clonidine orally. Sedation score (0 to 5) measured by using eyes condition, response to voice, and response to touch. Successful sedation, EEG performing, and hemodynamic stability were evaluated during sedation. Of all patients, 40 patients (88.88%) were sedated successfully, and EEG was performed for all of the children. Mean onset time of clonidine effect was 35.47±13.56 minutes and mean time of that the patients’ level of consciousness back to the level before administrating of clonidine was 77.55±26.87 minutes. Hemodynamic states of all patients were stable during the study, and there were no significant changes in vital sign of patients. In conclusion, clonidine can be considered as a safe alternative medication for sedation for EEG, which is fortunately associated with no significant change in vital signs, which may complicate overall status of patients.

OriginalsprogEngelsk
TidsskriftActa Medica Iranica
Vol/bind55
Udgave nummer9
Sider (fra-til)568-572
ISSN0044-6025
StatusUdgivet - 1. jan. 2017
Udgivet eksterntJa

Fingeraftryk

Clonidine
Electroencephalography
Vital Signs
Consciousness
Randomized Controlled Trials

Citer dette

Barzegar, Mohammad ; Piri, Reza ; Naghavi-Behzad, Mohammad ; Ghasempour, Masoumeh. / Clonidine sedation effects in children during electroencephalography. I: Acta Medica Iranica. 2017 ; Bind 55, Nr. 9. s. 568-572.
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Clonidine sedation effects in children during electroencephalography. / Barzegar, Mohammad; Piri, Reza; Naghavi-Behzad, Mohammad; Ghasempour, Masoumeh.

I: Acta Medica Iranica, Bind 55, Nr. 9, 01.01.2017, s. 568-572.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Clonidine sedation effects in children during electroencephalography

AU - Barzegar, Mohammad

AU - Piri, Reza

AU - Naghavi-Behzad, Mohammad

AU - Ghasempour, Masoumeh

PY - 2017/1/1

Y1 - 2017/1/1

N2 - It is very important to have proper management in children with Seizure. Electroencephalography (EEG) as a diagnostic instrument has a key role in determining the management method of seizure in children. Because of poor cooperation of some children (especially children with attention deficit hyperactivity disorders and developmental disorders) in performing EEG, it is the best choice to sedate children before EEG. The aim of present study is to evaluate the sedation efficacy of clonidine in children before EEG. In a randomized clinical trial, 45 children age 2 to 12 with seizure, who referred to Children Hospital of Tabriz University of Medical Sciences and candidate for EEG, were studied. Sedation before EEG induced by 0.5 to 2.0 mg clonidine orally. Sedation score (0 to 5) measured by using eyes condition, response to voice, and response to touch. Successful sedation, EEG performing, and hemodynamic stability were evaluated during sedation. Of all patients, 40 patients (88.88%) were sedated successfully, and EEG was performed for all of the children. Mean onset time of clonidine effect was 35.47±13.56 minutes and mean time of that the patients’ level of consciousness back to the level before administrating of clonidine was 77.55±26.87 minutes. Hemodynamic states of all patients were stable during the study, and there were no significant changes in vital sign of patients. In conclusion, clonidine can be considered as a safe alternative medication for sedation for EEG, which is fortunately associated with no significant change in vital signs, which may complicate overall status of patients.

AB - It is very important to have proper management in children with Seizure. Electroencephalography (EEG) as a diagnostic instrument has a key role in determining the management method of seizure in children. Because of poor cooperation of some children (especially children with attention deficit hyperactivity disorders and developmental disorders) in performing EEG, it is the best choice to sedate children before EEG. The aim of present study is to evaluate the sedation efficacy of clonidine in children before EEG. In a randomized clinical trial, 45 children age 2 to 12 with seizure, who referred to Children Hospital of Tabriz University of Medical Sciences and candidate for EEG, were studied. Sedation before EEG induced by 0.5 to 2.0 mg clonidine orally. Sedation score (0 to 5) measured by using eyes condition, response to voice, and response to touch. Successful sedation, EEG performing, and hemodynamic stability were evaluated during sedation. Of all patients, 40 patients (88.88%) were sedated successfully, and EEG was performed for all of the children. Mean onset time of clonidine effect was 35.47±13.56 minutes and mean time of that the patients’ level of consciousness back to the level before administrating of clonidine was 77.55±26.87 minutes. Hemodynamic states of all patients were stable during the study, and there were no significant changes in vital sign of patients. In conclusion, clonidine can be considered as a safe alternative medication for sedation for EEG, which is fortunately associated with no significant change in vital signs, which may complicate overall status of patients.

KW - Clonidine

KW - Electroencephalography

KW - Sedation

M3 - Journal article

AN - SCOPUS:85032963200

VL - 55

SP - 568

EP - 572

JO - Acta Medica Iranica

JF - Acta Medica Iranica

SN - 0044-6025

IS - 9

ER -