Clinical characteristics and consequences of hand eczema - an 8-year follow-up study of a population-based twin cohort

Anne Lerbaek, Kirsten Ohm Kyvik, Henrik Ravn, Torkil Menné, Tove Agner

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Udgivelsesdato: 2008-Apr
OriginalsprogEngelsk
TidsskriftContact Dermatitis
Vol/bind58
Udgave nummer4
Sider (fra-til)210-216
Antal sider6
ISSN0105-1873
DOI
StatusUdgivet - 1. apr. 2008

Fingeraftryk

Eczema
Population
Sick Leave
Odds Ratio
Confidence Intervals
Atopic Dermatitis
Erythema

Citer dette

@article{a19da470411311dd9fbe000ea68e967b,
title = "Clinical characteristics and consequences of hand eczema - an 8-year follow-up study of a population-based twin cohort",
abstract = "BACKGROUND: Few population-based clinical follow-up studies on hand eczema are reported. Objectives: The aim of this study was to characterize clinical symptoms and to examine occupational and medical consequences as well as persistence of hand eczema in a population-based twin cohort. PATIENTS/METHODS: A total of 274 individuals with and without hand eczema were examined, patch tested, and interviewed in 1997-1998 and 2005-2006. Data on 188 individuals with hand eczema in 2005-2006 were analysed. RESULTS: Erythema and scaling were the most frequent symptoms, and fingers and palms were most often affected. Mean hand eczema severity index score in individuals with clinical symptoms was 12.0. Sick leave was reported by 12.4{\%}; job change by 8.5{\%}. Being in the lowest socio-economic group and atopic dermatitis were risk factors for sick leave [odds ratio (OR) = 5.6; 95{\%} confidence interval (95{\%} CI) 1.5-22.9 and OR = 2.9; 95{\%} CI 1.0-8.1]. The majority (63.4{\%}) had seen a doctor at least once, and atopic dermatitis was a risk factor for more than 1 visit (OR = 3.0; 95{\%} CI 1.4-6.4). Duration of >10 years was a risk factor for persistence of symptoms, which was reported by 67.7{\%}. CONCLUSIONS: The clinical picture and consequences of hand eczema vary; however, the majority experience chronic symptoms.",
keywords = "Adult, Denmark, Dermatitis, Atopic, Diseases in Twins, Eczema, Female, Follow-Up Studies, Hand, Hand Dermatoses, Humans, Interviews as Topic, Logistic Models, Male, Middle Aged, Patch Tests, Patient Acceptance of Health Care, Risk Factors, Severity of Illness Index, Sick Leave, Skin, Socioeconomic Factors, Twins, Dizygotic, Twins, Monozygotic",
author = "Anne Lerbaek and Kyvik, {Kirsten Ohm} and Henrik Ravn and Torkil Menn{\'e} and Tove Agner",
year = "2008",
month = "4",
day = "1",
doi = "10.1111/j.1600-0536.2007.01305.x",
language = "English",
volume = "58",
pages = "210--216",
journal = "Contact Dermatitis",
issn = "0105-1873",
publisher = "Wiley-Blackwell",
number = "4",

}

Clinical characteristics and consequences of hand eczema - an 8-year follow-up study of a population-based twin cohort. / Lerbaek, Anne; Kyvik, Kirsten Ohm; Ravn, Henrik; Menné, Torkil; Agner, Tove.

I: Contact Dermatitis, Bind 58, Nr. 4, 01.04.2008, s. 210-216.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Clinical characteristics and consequences of hand eczema - an 8-year follow-up study of a population-based twin cohort

AU - Lerbaek, Anne

AU - Kyvik, Kirsten Ohm

AU - Ravn, Henrik

AU - Menné, Torkil

AU - Agner, Tove

PY - 2008/4/1

Y1 - 2008/4/1

N2 - BACKGROUND: Few population-based clinical follow-up studies on hand eczema are reported. Objectives: The aim of this study was to characterize clinical symptoms and to examine occupational and medical consequences as well as persistence of hand eczema in a population-based twin cohort. PATIENTS/METHODS: A total of 274 individuals with and without hand eczema were examined, patch tested, and interviewed in 1997-1998 and 2005-2006. Data on 188 individuals with hand eczema in 2005-2006 were analysed. RESULTS: Erythema and scaling were the most frequent symptoms, and fingers and palms were most often affected. Mean hand eczema severity index score in individuals with clinical symptoms was 12.0. Sick leave was reported by 12.4%; job change by 8.5%. Being in the lowest socio-economic group and atopic dermatitis were risk factors for sick leave [odds ratio (OR) = 5.6; 95% confidence interval (95% CI) 1.5-22.9 and OR = 2.9; 95% CI 1.0-8.1]. The majority (63.4%) had seen a doctor at least once, and atopic dermatitis was a risk factor for more than 1 visit (OR = 3.0; 95% CI 1.4-6.4). Duration of >10 years was a risk factor for persistence of symptoms, which was reported by 67.7%. CONCLUSIONS: The clinical picture and consequences of hand eczema vary; however, the majority experience chronic symptoms.

AB - BACKGROUND: Few population-based clinical follow-up studies on hand eczema are reported. Objectives: The aim of this study was to characterize clinical symptoms and to examine occupational and medical consequences as well as persistence of hand eczema in a population-based twin cohort. PATIENTS/METHODS: A total of 274 individuals with and without hand eczema were examined, patch tested, and interviewed in 1997-1998 and 2005-2006. Data on 188 individuals with hand eczema in 2005-2006 were analysed. RESULTS: Erythema and scaling were the most frequent symptoms, and fingers and palms were most often affected. Mean hand eczema severity index score in individuals with clinical symptoms was 12.0. Sick leave was reported by 12.4%; job change by 8.5%. Being in the lowest socio-economic group and atopic dermatitis were risk factors for sick leave [odds ratio (OR) = 5.6; 95% confidence interval (95% CI) 1.5-22.9 and OR = 2.9; 95% CI 1.0-8.1]. The majority (63.4%) had seen a doctor at least once, and atopic dermatitis was a risk factor for more than 1 visit (OR = 3.0; 95% CI 1.4-6.4). Duration of >10 years was a risk factor for persistence of symptoms, which was reported by 67.7%. CONCLUSIONS: The clinical picture and consequences of hand eczema vary; however, the majority experience chronic symptoms.

KW - Adult

KW - Denmark

KW - Dermatitis, Atopic

KW - Diseases in Twins

KW - Eczema

KW - Female

KW - Follow-Up Studies

KW - Hand

KW - Hand Dermatoses

KW - Humans

KW - Interviews as Topic

KW - Logistic Models

KW - Male

KW - Middle Aged

KW - Patch Tests

KW - Patient Acceptance of Health Care

KW - Risk Factors

KW - Severity of Illness Index

KW - Sick Leave

KW - Skin

KW - Socioeconomic Factors

KW - Twins, Dizygotic

KW - Twins, Monozygotic

U2 - 10.1111/j.1600-0536.2007.01305.x

DO - 10.1111/j.1600-0536.2007.01305.x

M3 - Journal article

VL - 58

SP - 210

EP - 216

JO - Contact Dermatitis

JF - Contact Dermatitis

SN - 0105-1873

IS - 4

ER -