Circulating osteogenic cells: implications for injury, repair, and regeneration

Robert J Pignolo, Moustapha Kassem

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

The aim of this review is to provide a critical reading of recent literature pertaining to the presence of circulating, fluid-phase osteoblastic cells and their possible contribution to bone formation. We have termed this group of cells collectively as circulating osteogenic precursor (COP) cells. We present evidence for their existence, methods used for their isolation and identification, possible physiological and pathophysiological roles, cellular origins, and possible mechanisms for their migration to target tissues.
OriginalsprogEngelsk
TidsskriftJournal of Bone and Mineral Research
Vol/bind26
Udgave nummer8
Sider (fra-til)1685-93
Antal sider9
ISSN0884-0431
DOI
StatusUdgivet - 2011

Fingeraftryk

Wounds and Injuries
Osteogenesis
Reading

Citer dette

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abstract = "The aim of this review is to provide a critical reading of recent literature pertaining to the presence of circulating, fluid-phase osteoblastic cells and their possible contribution to bone formation. We have termed this group of cells collectively as circulating osteogenic precursor (COP) cells. We present evidence for their existence, methods used for their isolation and identification, possible physiological and pathophysiological roles, cellular origins, and possible mechanisms for their migration to target tissues.",
keywords = "Animals, Cell Movement, Humans, Osteoblasts, Osteogenesis, Regeneration, Stem Cells, Wound Healing",
author = "Pignolo, {Robert J} and Moustapha Kassem",
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Circulating osteogenic cells: implications for injury, repair, and regeneration. / Pignolo, Robert J; Kassem, Moustapha.

I: Journal of Bone and Mineral Research, Bind 26, Nr. 8, 2011, s. 1685-93.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Circulating osteogenic cells: implications for injury, repair, and regeneration

AU - Pignolo, Robert J

AU - Kassem, Moustapha

N1 - Copyright © 2011 American Society for Bone and Mineral Research.

PY - 2011

Y1 - 2011

N2 - The aim of this review is to provide a critical reading of recent literature pertaining to the presence of circulating, fluid-phase osteoblastic cells and their possible contribution to bone formation. We have termed this group of cells collectively as circulating osteogenic precursor (COP) cells. We present evidence for their existence, methods used for their isolation and identification, possible physiological and pathophysiological roles, cellular origins, and possible mechanisms for their migration to target tissues.

AB - The aim of this review is to provide a critical reading of recent literature pertaining to the presence of circulating, fluid-phase osteoblastic cells and their possible contribution to bone formation. We have termed this group of cells collectively as circulating osteogenic precursor (COP) cells. We present evidence for their existence, methods used for their isolation and identification, possible physiological and pathophysiological roles, cellular origins, and possible mechanisms for their migration to target tissues.

KW - Animals

KW - Cell Movement

KW - Humans

KW - Osteoblasts

KW - Osteogenesis

KW - Regeneration

KW - Stem Cells

KW - Wound Healing

U2 - 10.1002/jbmr.370

DO - 10.1002/jbmr.370

M3 - Journal article

C2 - 21538513

VL - 26

SP - 1685

EP - 1693

JO - Journal of Bone and Mineral Research

JF - Journal of Bone and Mineral Research

SN - 0884-0431

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