Chondromalacia induced by patellar subluxation in the rabbit

B.N. Møller, F. Møller-Larsen, Lars Henrik Frich

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

A unilateral patellar malalignment was induced in 20 young and 20 mature rabbits by lateral displacement of the tibial tuberosity, the other knee serving as osteotomized in situ control. At 6 weeks, all the knees appeared macroscopically normal, but histologically definite cartilage degeneration was found on the experimental side. At 3 months, macroscopic changes occurred in 5 of 10 mature rabbits, and histologic cartilage degeneration was found in all the experimental knees, most pronounced in mature animals, and particularly in joint facets submitted to high pressure. This experimental model produces changes resembling chondromalacia patellae and early arthrotic changes suggesting the importance of malalignment in the development of patellofemoral cartilage degeneration.
OriginalsprogEngelsk
TidsskriftActa Orthopaedica Scandinavica
Vol/bind60
Udgave nummer2
Sider (fra-til)188-91
ISSN0001-6470
StatusUdgivet - 1989

Citer dette

Møller, B.N. ; Møller-Larsen, F. ; Frich, Lars Henrik. / Chondromalacia induced by patellar subluxation in the rabbit. I: Acta Orthopaedica Scandinavica. 1989 ; Bind 60, Nr. 2. s. 188-91.
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abstract = "A unilateral patellar malalignment was induced in 20 young and 20 mature rabbits by lateral displacement of the tibial tuberosity, the other knee serving as osteotomized in situ control. At 6 weeks, all the knees appeared macroscopically normal, but histologically definite cartilage degeneration was found on the experimental side. At 3 months, macroscopic changes occurred in 5 of 10 mature rabbits, and histologic cartilage degeneration was found in all the experimental knees, most pronounced in mature animals, and particularly in joint facets submitted to high pressure. This experimental model produces changes resembling chondromalacia patellae and early arthrotic changes suggesting the importance of malalignment in the development of patellofemoral cartilage degeneration.",
author = "B.N. M{\o}ller and F. M{\o}ller-Larsen and Frich, {Lars Henrik}",
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Møller, BN, Møller-Larsen, F & Frich, LH 1989, 'Chondromalacia induced by patellar subluxation in the rabbit', Acta Orthopaedica Scandinavica, bind 60, nr. 2, s. 188-91.

Chondromalacia induced by patellar subluxation in the rabbit. / Møller, B.N.; Møller-Larsen, F.; Frich, Lars Henrik.

I: Acta Orthopaedica Scandinavica, Bind 60, Nr. 2, 1989, s. 188-91.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Chondromalacia induced by patellar subluxation in the rabbit

AU - Møller, B.N.

AU - Møller-Larsen, F.

AU - Frich, Lars Henrik

PY - 1989

Y1 - 1989

N2 - A unilateral patellar malalignment was induced in 20 young and 20 mature rabbits by lateral displacement of the tibial tuberosity, the other knee serving as osteotomized in situ control. At 6 weeks, all the knees appeared macroscopically normal, but histologically definite cartilage degeneration was found on the experimental side. At 3 months, macroscopic changes occurred in 5 of 10 mature rabbits, and histologic cartilage degeneration was found in all the experimental knees, most pronounced in mature animals, and particularly in joint facets submitted to high pressure. This experimental model produces changes resembling chondromalacia patellae and early arthrotic changes suggesting the importance of malalignment in the development of patellofemoral cartilage degeneration.

AB - A unilateral patellar malalignment was induced in 20 young and 20 mature rabbits by lateral displacement of the tibial tuberosity, the other knee serving as osteotomized in situ control. At 6 weeks, all the knees appeared macroscopically normal, but histologically definite cartilage degeneration was found on the experimental side. At 3 months, macroscopic changes occurred in 5 of 10 mature rabbits, and histologic cartilage degeneration was found in all the experimental knees, most pronounced in mature animals, and particularly in joint facets submitted to high pressure. This experimental model produces changes resembling chondromalacia patellae and early arthrotic changes suggesting the importance of malalignment in the development of patellofemoral cartilage degeneration.

M3 - Journal article

VL - 60

SP - 188

EP - 191

JO - Acta Orthopaedica Scandinavica

JF - Acta Orthopaedica Scandinavica

SN - 0001-6470

IS - 2

ER -