Characterisation of a multidrug-resistant Bacteroides fragilis isolate recovered from blood of a patient in Denmark using whole-genome sequencing

Nina Ank; Thomas V Sydenham; Lene H Iversen; Ulrik S Justesen; Mikala Wang

doi:10.1016/j.ijantimicag.2015.02.024

Characterisation of a multidrug-resistant Bacteroides fragilis isolate recovered from blood of a patient in Denmark using whole-genome sequencing

Nina Ank, Thomas V Sydenham, Lene H Iversen, Ulrik S Justesen, Mikala Wang

KI, Klinisk Mikrobiologi

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Abstrakt

Here we describe a patient undergoing extensive abdominal surgery and hyperthermic intraperitoneal chemotherapy due to primary adenocarcinoma in the sigmoid colon with peritoneal carcinomatosis. During hospitalisation the patient suffered from bacteraemia with a multidrug-resistant Bacteroides fragilis isolate. Whole-genome sequencing of the isolate resulted in identification of nimE, cfiA and ermF genes corresponding to metronidazole, carbapenem and clindamycin resistance.

Originalsprog	Engelsk
Tidsskrift	International Journal of Antimicrobial Agents
Vol/bind	46
Udgave nummer	1
Sider (fra-til)	117-120
ISSN	0924-8579
DOI	https://doi.org/10.1016/j.ijantimicag.2015.02.024
Status	Udgivet - 2015

Dokumenter og links

10.1016/j.ijantimicag.2015.02.024

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Citationsformater

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author = "Nina Ank and Sydenham, {Thomas V} and Iversen, {Lene H} and Justesen, {Ulrik S} and Mikala Wang",

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Characterisation of a multidrug-resistant Bacteroides fragilis isolate recovered from blood of a patient in Denmark using whole-genome sequencing. / Ank, Nina; Sydenham, Thomas V; Iversen, Lene H; Justesen, Ulrik S; Wang, Mikala.

I: International Journal of Antimicrobial Agents, Bind 46, Nr. 1, 2015, s. 117-120.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

TY - JOUR

T1 - Characterisation of a multidrug-resistant Bacteroides fragilis isolate recovered from blood of a patient in Denmark using whole-genome sequencing

AU - Ank, Nina

AU - Sydenham, Thomas V

AU - Iversen, Lene H

AU - Justesen, Ulrik S

AU - Wang, Mikala

PY - 2015

Y1 - 2015

N2 - Here we describe a patient undergoing extensive abdominal surgery and hyperthermic intraperitoneal chemotherapy due to primary adenocarcinoma in the sigmoid colon with peritoneal carcinomatosis. During hospitalisation the patient suffered from bacteraemia with a multidrug-resistant Bacteroides fragilis isolate. Whole-genome sequencing of the isolate resulted in identification of nimE, cfiA and ermF genes corresponding to metronidazole, carbapenem and clindamycin resistance.

AB - Here we describe a patient undergoing extensive abdominal surgery and hyperthermic intraperitoneal chemotherapy due to primary adenocarcinoma in the sigmoid colon with peritoneal carcinomatosis. During hospitalisation the patient suffered from bacteraemia with a multidrug-resistant Bacteroides fragilis isolate. Whole-genome sequencing of the isolate resulted in identification of nimE, cfiA and ermF genes corresponding to metronidazole, carbapenem and clindamycin resistance.

U2 - 10.1016/j.ijantimicag.2015.02.024

DO - 10.1016/j.ijantimicag.2015.02.024

M3 - Journal article

C2 - 25940770

VL - 46

SP - 117

EP - 120

JO - International Journal of Antimicrobial Agents

JF - International Journal of Antimicrobial Agents

SN - 0924-8579

IS - 1

ER -