Cardiovascular disease and long-term occupational exposure to ultrafine particles: A cohort study of airport workers

Karina Lauenborg Møller*, Charlotte Brauer, Sigurd Mikkelsen, Jens Peter Bonde, Steffen Loft, Karin Helweg-Larsen, Lau Caspar Thygesen

*Kontaktforfatter for dette arbejde

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

AIM: To investigate if ischemic heart disease (IHD) and cerebrovascular disease is associated with long-term occupational exposure to ultrafine particles (UFP) outdoors at an airport.

METHODS AND RESULTS: This is a register-based follow-up study based on a cohort comprising an exposed group of 6515 men employed in unskilled work at Copenhagen Airport and a reference group of 61,617 men in unskilled work in other firms in greater Copenhagen during 1990-2012. The exposure was assessed from information on proportion of time spent on the airport apron for each calendar year (apron-years) and the primary exposure measure was cumulated apron-years. The cohort was merged to the National Patient Register that includes data on all contacts to public and private hospitals in Denmark and the Register of Causes of Death. Risk estimates were provided by Poisson regression and adjusted for age, calendar year and educational level. We found no associations between cumulative apron-years and IHD (IRR, 1.00; 95%CI, 0.97-1.03) or cerebrovascular disease (IRR, 1.00; 0.98-1.02) when adjusted for confounders.

CONCLUSION: In this large cohort study, we found no association between outdoor occupational exposure to UFP and IHD and cerebrovascular disease.

OriginalsprogEngelsk
TidsskriftInternational Journal of Hygiene and Environmental Health
Vol/bind223
Udgave nummer1
Sider (fra-til)214-219
ISSN1438-4639
DOI
StatusUdgivet - 1. jan. 2020

Fingeraftryk

Occupational Exposure
Cohort Studies
Private Hospitals
Public Hospitals
Denmark
Cause of Death
Ultrafine
insulin receptor-related receptor

Bibliografisk note

Copyright © 2019. Published by Elsevier GmbH.

Citer dette

Møller, Karina Lauenborg ; Brauer, Charlotte ; Mikkelsen, Sigurd ; Bonde, Jens Peter ; Loft, Steffen ; Helweg-Larsen, Karin ; Thygesen, Lau Caspar. / Cardiovascular disease and long-term occupational exposure to ultrafine particles : A cohort study of airport workers. I: International Journal of Hygiene and Environmental Health. 2020 ; Bind 223, Nr. 1. s. 214-219.
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abstract = "AIM: To investigate if ischemic heart disease (IHD) and cerebrovascular disease is associated with long-term occupational exposure to ultrafine particles (UFP) outdoors at an airport.METHODS AND RESULTS: This is a register-based follow-up study based on a cohort comprising an exposed group of 6515 men employed in unskilled work at Copenhagen Airport and a reference group of 61,617 men in unskilled work in other firms in greater Copenhagen during 1990-2012. The exposure was assessed from information on proportion of time spent on the airport apron for each calendar year (apron-years) and the primary exposure measure was cumulated apron-years. The cohort was merged to the National Patient Register that includes data on all contacts to public and private hospitals in Denmark and the Register of Causes of Death. Risk estimates were provided by Poisson regression and adjusted for age, calendar year and educational level. We found no associations between cumulative apron-years and IHD (IRR, 1.00; 95{\%}CI, 0.97-1.03) or cerebrovascular disease (IRR, 1.00; 0.98-1.02) when adjusted for confounders.CONCLUSION: In this large cohort study, we found no association between outdoor occupational exposure to UFP and IHD and cerebrovascular disease.",
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Cardiovascular disease and long-term occupational exposure to ultrafine particles : A cohort study of airport workers. / Møller, Karina Lauenborg; Brauer, Charlotte; Mikkelsen, Sigurd; Bonde, Jens Peter; Loft, Steffen; Helweg-Larsen, Karin; Thygesen, Lau Caspar.

I: International Journal of Hygiene and Environmental Health, Bind 223, Nr. 1, 01.01.2020, s. 214-219.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Cardiovascular disease and long-term occupational exposure to ultrafine particles

T2 - A cohort study of airport workers

AU - Møller, Karina Lauenborg

AU - Brauer, Charlotte

AU - Mikkelsen, Sigurd

AU - Bonde, Jens Peter

AU - Loft, Steffen

AU - Helweg-Larsen, Karin

AU - Thygesen, Lau Caspar

N1 - Copyright © 2019. Published by Elsevier GmbH.

PY - 2020/1/1

Y1 - 2020/1/1

N2 - AIM: To investigate if ischemic heart disease (IHD) and cerebrovascular disease is associated with long-term occupational exposure to ultrafine particles (UFP) outdoors at an airport.METHODS AND RESULTS: This is a register-based follow-up study based on a cohort comprising an exposed group of 6515 men employed in unskilled work at Copenhagen Airport and a reference group of 61,617 men in unskilled work in other firms in greater Copenhagen during 1990-2012. The exposure was assessed from information on proportion of time spent on the airport apron for each calendar year (apron-years) and the primary exposure measure was cumulated apron-years. The cohort was merged to the National Patient Register that includes data on all contacts to public and private hospitals in Denmark and the Register of Causes of Death. Risk estimates were provided by Poisson regression and adjusted for age, calendar year and educational level. We found no associations between cumulative apron-years and IHD (IRR, 1.00; 95%CI, 0.97-1.03) or cerebrovascular disease (IRR, 1.00; 0.98-1.02) when adjusted for confounders.CONCLUSION: In this large cohort study, we found no association between outdoor occupational exposure to UFP and IHD and cerebrovascular disease.

AB - AIM: To investigate if ischemic heart disease (IHD) and cerebrovascular disease is associated with long-term occupational exposure to ultrafine particles (UFP) outdoors at an airport.METHODS AND RESULTS: This is a register-based follow-up study based on a cohort comprising an exposed group of 6515 men employed in unskilled work at Copenhagen Airport and a reference group of 61,617 men in unskilled work in other firms in greater Copenhagen during 1990-2012. The exposure was assessed from information on proportion of time spent on the airport apron for each calendar year (apron-years) and the primary exposure measure was cumulated apron-years. The cohort was merged to the National Patient Register that includes data on all contacts to public and private hospitals in Denmark and the Register of Causes of Death. Risk estimates were provided by Poisson regression and adjusted for age, calendar year and educational level. We found no associations between cumulative apron-years and IHD (IRR, 1.00; 95%CI, 0.97-1.03) or cerebrovascular disease (IRR, 1.00; 0.98-1.02) when adjusted for confounders.CONCLUSION: In this large cohort study, we found no association between outdoor occupational exposure to UFP and IHD and cerebrovascular disease.

KW - Airport

KW - Cardiovascular disease

KW - Epidemiology

KW - Occupational exposure

KW - Ultrafine particles

U2 - 10.1016/j.ijheh.2019.08.010

DO - 10.1016/j.ijheh.2019.08.010

M3 - Journal article

C2 - 31492618

VL - 223

SP - 214

EP - 219

JO - International Journal of Hygiene and Environmental Health

JF - International Journal of Hygiene and Environmental Health

SN - 1438-4639

IS - 1

ER -