Cancergenetisk rådgivningsklinik. Erfaringer med genetisk udredning og rådgivning ved familiaer cancer mammae og familiaer cancer colorectalis

A M Gerdes, K Rasmussen, H P Graversen, O Kronborg, N Qvist, N V Holm, C K Axelsson, C Rose, S Ahrons, U Dyreborg, M Hørder

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstrakt

Five to ten percent of cases of breast cancer and colorectal cancer are familial. These families can be divided into high-risk families and moderate-risk families. Cancer in high-risk families can often be explained by dominant inheritance of a gene causing increased susceptibility to cancer. There is a great demand for genetic counseling in these families, and the structure of and experiences from a familial cancer clinic at Odense University Hospital is described. The establishment of a familial cancer clinic involves three steps: 1) Identification of families with increased cancer susceptibility; 2) Molecular tests to identify gene carriers; 3) Clinical examinations for early detection of tumors. Achievement of these three steps requires the involvement of several medical specialties to ensure patient care. Experience with familial cancer clinics is still limited and the involvement of genetic testing and clinical examination programs at risk individuals are insufficiently examined. The rapidly improving techniques for genetic testing make it urgent that it is implemented as part of already established clinical programs.
Bidragets oversatte titelClinics for counseling on cancer genetics. Experiences with genetic studies and counseling on familial breast cancer and colorectal cancer
OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind160
Udgave nummer8
Sider (fra-til)1145-51
Antal sider7
ISSN0041-5782
StatusUdgivet - 16. feb. 1998

Emneord

  • Adult
  • Aged
  • Breast Neoplasms
  • Colonic Neoplasms
  • Denmark
  • Female
  • Genetic Counseling
  • Genetic Testing
  • Humans
  • Male
  • Middle Aged
  • Pedigree
  • Rectal Neoplasms

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  • Citationsformater

    Gerdes, A. M., Rasmussen, K., Graversen, H. P., Kronborg, O., Qvist, N., Holm, N. V., Axelsson, C. K., Rose, C., Ahrons, S., Dyreborg, U., & Hørder, M. (1998). Cancergenetisk rådgivningsklinik. Erfaringer med genetisk udredning og rådgivning ved familiaer cancer mammae og familiaer cancer colorectalis. Ugeskrift for Laeger, 160(8), 1145-51.