Can Ultrasound Elastography Discriminate between Rectal Adenoma and Cancer? A Systematic Review

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

6 Downloads (Pure)

Abstrakt

Background: Rectal cancer is a common malignancy. Since the introduction of bowel-screening programs, the number of patients with advanced adenomas and early rectal cancer has increased. Despite improved diagnostics, the discrimination between rectal adenomas and early rectal cancer (i.e., pT1–T2) remains challenging. The purpose of this systematic review was to evaluate the diagnostic performance of endorectal ultrasound (ERUS) elastography in discriminating rectal adenomas from cancer. Method: Using PRISMA guidelines, a systematic search was performed on PubMed, Embase, and MEDLINE databases. Studies evaluating the primary staging of rectal adenomas and cancer using ERUS elastography were included. Results: Six studies were identified; three evaluated the discrimination between adenomas and cancer; two evaluated adenomas and early rectal cancer (i.e., pT1–T2); one evaluated performance on different T categories. All studies reported increased diagnostic accuracy of ERUS elastography compared to ERUS. Sensitivity, specificity and accuracy ranged 0.93–1.00, 0.83–1.00 and 0.91–1.00, respectively, when discriminating adenomas from cancer. In the differentiation between adenomas and early rectal cancer, the sensitivity, specificity and accuracy were 0.82–1.00, 0.86–1.00 and 0.84–1.00, respectively. Conclusion: Elastography increases the accuracy of ERUS and may provide valuable information on malignant transformation of rectal lesions
OriginalsprogEngelsk
Artikelnummer4158
TidsskriftCancers
Vol/bind13
Udgave nummer16
Antal sider12
ISSN2072-6694
DOI
StatusUdgivet - 18. aug. 2021

Fingeraftryk

Dyk ned i forskningsemnerne om 'Can Ultrasound Elastography Discriminate between Rectal Adenoma and Cancer? A Systematic Review'. Sammen danner de et unikt fingeraftryk.

Citationsformater