Bone Mass Development in Childhood and Its Association with Physical Activity and Vitamin D Levels

The CHAMPS-Study DK

Maria Sode Rønne*, Malene Heidemann, Louise Lylloff, Anders J Schou, Jakob Tarp, Jens Ole Laursen, Niklas Rye Jørgensen, Steffen Husby, Niels Wedderkopp, Christian Mølgaard

*Kontaktforfatter for dette arbejde

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Resumé

This longitudinal study examined associations of bone mass with physical activity and vitamin D level over more than 6 years through puberty. A total of 663 participants (320 boys) with mean age 9.6 years at baseline (10-17 years at follow-up), underwent dual energy X-ray absorptiometry, anthropometry and blood samples for vitamin D at least twice during the study period (with three possible time-points). Physical activity was assessed using accelerometers at follow-up. A positive association was found between percent time spent at vigorous physical activity and total-body less head bone mineral content (β = 5.8, p = 0.002). The magnitude of this association increased with maturational development; thus physical activity may have a greater influence on bone mass in the more mature participants. The vitamin D levels were also positively associated with bone mass. A high degree of tracking was observed with changes in anthropometric Z scores predictive of deviation from tracking. No environmental factor predicted deviation from tracking.

OriginalsprogEngelsk
TidsskriftCalcified Tissue International
Vol/bind104
Udgave nummer1
Sider (fra-til)1-13
ISSN0171-967X
DOI
StatusUdgivet - jan. 2019

Fingeraftryk

Exercise
Photon Absorptiometry
Bone Density
Longitudinal Studies

Citer dette

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title = "Bone Mass Development in Childhood and Its Association with Physical Activity and Vitamin D Levels: The CHAMPS-Study DK",
abstract = "This longitudinal study examined associations of bone mass with physical activity and vitamin D level over more than 6 years through puberty. A total of 663 participants (320 boys) with mean age 9.6 years at baseline (10-17 years at follow-up), underwent dual energy X-ray absorptiometry, anthropometry and blood samples for vitamin D at least twice during the study period (with three possible time-points). Physical activity was assessed using accelerometers at follow-up. A positive association was found between percent time spent at vigorous physical activity and total-body less head bone mineral content (β = 5.8, p = 0.002). The magnitude of this association increased with maturational development; thus physical activity may have a greater influence on bone mass in the more mature participants. The vitamin D levels were also positively associated with bone mass. A high degree of tracking was observed with changes in anthropometric Z scores predictive of deviation from tracking. No environmental factor predicted deviation from tracking.",
keywords = "Bone mass, Dual energy X-ray absorptiometry, Physical activity, Puberty, Tracking, Vitamin D",
author = "R{\o}nne, {Maria Sode} and Malene Heidemann and Louise Lylloff and Schou, {Anders J} and Jakob Tarp and Laursen, {Jens Ole} and J{\o}rgensen, {Niklas Rye} and Steffen Husby and Niels Wedderkopp and Christian M{\o}lgaard",
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journal = "Calcified Tissue International",
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Bone Mass Development in Childhood and Its Association with Physical Activity and Vitamin D Levels : The CHAMPS-Study DK. / Rønne, Maria Sode; Heidemann, Malene; Lylloff, Louise; Schou, Anders J; Tarp, Jakob; Laursen, Jens Ole; Jørgensen, Niklas Rye; Husby, Steffen; Wedderkopp, Niels; Mølgaard, Christian.

I: Calcified Tissue International, Bind 104, Nr. 1, 01.2019, s. 1-13.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Bone Mass Development in Childhood and Its Association with Physical Activity and Vitamin D Levels

T2 - The CHAMPS-Study DK

AU - Rønne, Maria Sode

AU - Heidemann, Malene

AU - Lylloff, Louise

AU - Schou, Anders J

AU - Tarp, Jakob

AU - Laursen, Jens Ole

AU - Jørgensen, Niklas Rye

AU - Husby, Steffen

AU - Wedderkopp, Niels

AU - Mølgaard, Christian

PY - 2019/1

Y1 - 2019/1

N2 - This longitudinal study examined associations of bone mass with physical activity and vitamin D level over more than 6 years through puberty. A total of 663 participants (320 boys) with mean age 9.6 years at baseline (10-17 years at follow-up), underwent dual energy X-ray absorptiometry, anthropometry and blood samples for vitamin D at least twice during the study period (with three possible time-points). Physical activity was assessed using accelerometers at follow-up. A positive association was found between percent time spent at vigorous physical activity and total-body less head bone mineral content (β = 5.8, p = 0.002). The magnitude of this association increased with maturational development; thus physical activity may have a greater influence on bone mass in the more mature participants. The vitamin D levels were also positively associated with bone mass. A high degree of tracking was observed with changes in anthropometric Z scores predictive of deviation from tracking. No environmental factor predicted deviation from tracking.

AB - This longitudinal study examined associations of bone mass with physical activity and vitamin D level over more than 6 years through puberty. A total of 663 participants (320 boys) with mean age 9.6 years at baseline (10-17 years at follow-up), underwent dual energy X-ray absorptiometry, anthropometry and blood samples for vitamin D at least twice during the study period (with three possible time-points). Physical activity was assessed using accelerometers at follow-up. A positive association was found between percent time spent at vigorous physical activity and total-body less head bone mineral content (β = 5.8, p = 0.002). The magnitude of this association increased with maturational development; thus physical activity may have a greater influence on bone mass in the more mature participants. The vitamin D levels were also positively associated with bone mass. A high degree of tracking was observed with changes in anthropometric Z scores predictive of deviation from tracking. No environmental factor predicted deviation from tracking.

KW - Bone mass

KW - Dual energy X-ray absorptiometry

KW - Physical activity

KW - Puberty

KW - Tracking

KW - Vitamin D

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DO - 10.1007/s00223-018-0466-5

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