Biochemical Markers of Joint Tissue Turnover

Anne-Christine Bay-Jensen, Bodil Cecilie Sondergaard, Claus Christiansen, Morten A Karsdal, Suzi Høgh Madsen, Per Qvist

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Udgivelsesdato: 2009-Aug-29
OriginalsprogEngelsk
TidsskriftASSAY and Drug Development Technologies
Vol/bind8
Udgave nummer1
Sider (fra-til)118-124
ISSN1540-658X
DOI
StatusUdgivet - 29. aug. 2009

Fingeraftryk

Joints
Pharmaceutical Preparations

Citer dette

Bay-Jensen, A-C., Sondergaard, B. C., Christiansen, C., Karsdal, M. A., Madsen, S. H., & Qvist, P. (2009). Biochemical Markers of Joint Tissue Turnover. ASSAY and Drug Development Technologies, 8(1), 118-124. https://doi.org/10.1089/adt.2009.0199
Bay-Jensen, Anne-Christine ; Sondergaard, Bodil Cecilie ; Christiansen, Claus ; Karsdal, Morten A ; Madsen, Suzi Høgh ; Qvist, Per. / Biochemical Markers of Joint Tissue Turnover. I: ASSAY and Drug Development Technologies. 2009 ; Bind 8, Nr. 1. s. 118-124.
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title = "Biochemical Markers of Joint Tissue Turnover",
abstract = "Recent disappointments in late stage developments of anti-osteoarthritic drugs have reinforced efforts to develop better biomarkers for application in both the drug development process as well as in the routine management of these patients. Here we provide a brief review of biochemical tests available for the study of tissue turnover in each of the three compartments of the articular joint, that is the bone, the cartilage, and the synovium. Finally, we provide some perspective to future developments in biomarker discovery and discuss the potential impact such technologies could have on the drug development process.",
author = "Anne-Christine Bay-Jensen and Sondergaard, {Bodil Cecilie} and Claus Christiansen and Karsdal, {Morten A} and Madsen, {Suzi H{\o}gh} and Per Qvist",
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Bay-Jensen, A-C, Sondergaard, BC, Christiansen, C, Karsdal, MA, Madsen, SH & Qvist, P 2009, 'Biochemical Markers of Joint Tissue Turnover', ASSAY and Drug Development Technologies, bind 8, nr. 1, s. 118-124. https://doi.org/10.1089/adt.2009.0199

Biochemical Markers of Joint Tissue Turnover. / Bay-Jensen, Anne-Christine; Sondergaard, Bodil Cecilie; Christiansen, Claus; Karsdal, Morten A; Madsen, Suzi Høgh; Qvist, Per.

I: ASSAY and Drug Development Technologies, Bind 8, Nr. 1, 29.08.2009, s. 118-124.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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T1 - Biochemical Markers of Joint Tissue Turnover

AU - Bay-Jensen, Anne-Christine

AU - Sondergaard, Bodil Cecilie

AU - Christiansen, Claus

AU - Karsdal, Morten A

AU - Madsen, Suzi Høgh

AU - Qvist, Per

PY - 2009/8/29

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N2 - Recent disappointments in late stage developments of anti-osteoarthritic drugs have reinforced efforts to develop better biomarkers for application in both the drug development process as well as in the routine management of these patients. Here we provide a brief review of biochemical tests available for the study of tissue turnover in each of the three compartments of the articular joint, that is the bone, the cartilage, and the synovium. Finally, we provide some perspective to future developments in biomarker discovery and discuss the potential impact such technologies could have on the drug development process.

AB - Recent disappointments in late stage developments of anti-osteoarthritic drugs have reinforced efforts to develop better biomarkers for application in both the drug development process as well as in the routine management of these patients. Here we provide a brief review of biochemical tests available for the study of tissue turnover in each of the three compartments of the articular joint, that is the bone, the cartilage, and the synovium. Finally, we provide some perspective to future developments in biomarker discovery and discuss the potential impact such technologies could have on the drug development process.

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DO - 10.1089/adt.2009.0199

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Bay-Jensen A-C, Sondergaard BC, Christiansen C, Karsdal MA, Madsen SH, Qvist P. Biochemical Markers of Joint Tissue Turnover. ASSAY and Drug Development Technologies. 2009 aug 29;8(1):118-124. https://doi.org/10.1089/adt.2009.0199