Behandling og kontrol af B12-vitaminmangel

Emil Buhl; Bettina Borre Buhl; Linda Skibsted Kornerup; Ebba Nexø

doi:10.61409/V01240008

Behandling og kontrol af B12-vitaminmangel

Emil Buhl
, Bettina Borre Buhl
, Linda Skibsted Kornerup
, Ebba Nexø^*

^*Kontaktforfatter

Det Sundhedsvidenskabelige Fakultet

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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Abstract

No international treatment standard for B12 deficiency exists. Current practice predominantly relies on more than 50 years old data. Consequently, this review investigates that we still recommend five injections with 1 mg B12 over 10 days followed by maintenance therapy with 1 mg oral B12 daily or injections, of which the interval is guided by symptom relief rather than normalization of biomarkers. Clinical studies are highly warranted and should include formulation and administration of B12. Subcutaneous self-injection may prove cost-effective and benefit an individualized treatment strategy.

Bidragets oversatte titel	Vitamin B12 deficiency
Originalsprog	Dansk
Artikelnummer	V01240008
Tidsskrift	Ugeskrift for Læger
Vol/bind	186
Udgave nummer	19
ISSN	0041-5782
DOI	https://doi.org/10.61409/V01240008
Status	Udgivet - 30. sep. 2024

Emneord

Administration, Oral
Humans
Injections, Subcutaneous
Vitamin B 12 Deficiency/drug therapy
Vitamin B 12/administration & dosage

Dokumenter og links

10.61409/V01240008Licens: CC BY-NC-ND

Open Access VersionForlagets udgivne version, 374 KBLicens: CC BY-NC-ND

SDU link

Tjek adgangen til materialet i Syddansk Universitetsbiblioteks søgemaskine

Citationsformater

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AU - Buhl, Emil

AU - Buhl, Bettina Borre

AU - Kornerup, Linda Skibsted

AU - Nexø, Ebba

PY - 2024/9/30

Y1 - 2024/9/30

N2 - No international treatment standard for B12 deficiency exists. Current practice predominantly relies on more than 50 years old data. Consequently, this review investigates that we still recommend five injections with 1 mg B12 over 10 days followed by maintenance therapy with 1 mg oral B12 daily or injections, of which the interval is guided by symptom relief rather than normalization of biomarkers. Clinical studies are highly warranted and should include formulation and administration of B12. Subcutaneous self-injection may prove cost-effective and benefit an individualized treatment strategy.

AB - No international treatment standard for B12 deficiency exists. Current practice predominantly relies on more than 50 years old data. Consequently, this review investigates that we still recommend five injections with 1 mg B12 over 10 days followed by maintenance therapy with 1 mg oral B12 daily or injections, of which the interval is guided by symptom relief rather than normalization of biomarkers. Clinical studies are highly warranted and should include formulation and administration of B12. Subcutaneous self-injection may prove cost-effective and benefit an individualized treatment strategy.

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KW - Humans

KW - Injections, Subcutaneous

KW - Vitamin B 12 Deficiency/drug therapy

KW - Vitamin B 12/administration & dosage

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DO - 10.61409/V01240008

M3 - Tidsskriftartikel

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ER -

Behandling og kontrol af B12-vitaminmangel

Abstract

Emneord

Dokumenter og links

SDU link

Fingeraftryk

Citationsformater