Author Correction: Validation of the BOADICEA model for predicting the likelihood of carrying pathogenic variants in eight breast and ovarian cancer susceptibility genes (Scientific Reports, (2023), 13, 1, (8536), 10.1038/s41598-023-35755-8)

Nanna Bæk Møller; Desirée Sofie Boonen; Elisabeth Simone Feldner; Qin Hao; Martin Larsen; Anne Vibeke Lænkholm; Åke Borg; Anders Kvist; Therese Törngren; Uffe Birk Jensen; Susanne Eriksen Boonen; Mads Thomassen; Thorkild Terkelsen

doi:10.1038/s41598-023-42606-z

Author Correction: Validation of the BOADICEA model for predicting the likelihood of carrying pathogenic variants in eight breast and ovarian cancer susceptibility genes (Scientific Reports, (2023), 13, 1, (8536), 10.1038/s41598-023-35755-8)

Nanna Bæk Møller, Desirée Sofie Boonen, Elisabeth Simone Feldner, Qin Hao, Martin Larsen, Anne Vibeke Lænkholm, Åke Borg, Anders Kvist, Therese Törngren, Uffe Birk Jensen, Susanne Eriksen Boonen, Mads Thomassen^*, Thorkild Terkelsen^*

^*Kontaktforfatter

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Abstract

Correction to: Scientific Reports, published online 26 May 2023 The original version of this Article contained an error in Results section, under ‘Missing information’ subheading, “This did not significantly alter the calibration (O/E 1.11; 95% CI 0.97–1.26) or discrimination of the model (AUC 0.71; 95% CI).” now reads: “This did not significantly alter the calibration (O/E 1.11; 95% CI 0.97–1.26) or discrimination of the model (AUC 0.71; 95% CI 0.66–0.75).” Additionally, this Article contained errors in Table 3, where the sensitivity and specificity values for BRCA1/BRCA2 at CP ≥ 3% were incorrect. The correct and incorrect values appear below. Incorrect: (Table presented.) CP (%) All genes BRCA1/BRCA2 Other genes Sensitivity Specificity Sensitivity Specificity Sensitivity Specificity ≥ 0 1.00 0.000 1.00 0.000 1.00 0.000 ≥ 1 1.00 0.001 1.00 0.001 1.00 0.001 ≥ 2 0.98 0.072 0.98 0.071 0.97 0.068 ≥ 3 0.92 0.19 0.87 0.36 0.87 0.18 Correct: (Table presented.) CP (%) All genes BRCA1/BRCA2 Other genes Sensitivity Specificity Sensitivity Specificity Sensitivity Specificity ≥ 0 1.00 0.000 1.00 0.000 1.00 0.000 ≥ 1 1.00 0.001 1.00 0.001 1.00 0.001 ≥ 2 0.98 0.072 0.98 0.071 0.97 0.068 ≥ 3 0.92 0.19 0.95 0.19 0.87 0.18 The original Article has been corrected.

Originalsprog	Engelsk
Artikelnummer	15294
Tidsskrift	Scientific Reports
Vol/bind	13
Antal sider	2
ISSN	2045-2322
DOI	https://doi.org/10.1038/s41598-023-42606-z
Status	Udgivet - 15. sep. 2023

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10.1038/s41598-023-42606-zLicens: CC BY

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Validation of the BOADICEA model for predicting the likelihood of carrying pathogenic variants in eight breast and ovarian cancer susceptibility genes
Møller, N. B., Boonen, D. S., Feldner, E. S., Hao, Q., Larsen, M., Lænkholm, A.-V., Borg, Å., Kvist, A., Törngren, T., Jensen, U. B., Boonen, S. E., Thomassen, M. & Terkelsen, T., 26. maj 2023, I: Scientific Reports. 13, 8536.
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Møller, N. B., Boonen, D. S., Feldner, E. S., Hao, Q., Larsen, M., Lænkholm, A. V., Borg, Å., Kvist, A., Törngren, T., Jensen, U. B., Boonen, S. E., Thomassen, M., & Terkelsen, T. (2023). Author Correction: Validation of the BOADICEA model for predicting the likelihood of carrying pathogenic variants in eight breast and ovarian cancer susceptibility genes (Scientific Reports, (2023), 13, 1, (8536), 10.1038/s41598-023-35755-8). Scientific Reports, 13, Artikel 15294. https://doi.org/10.1038/s41598-023-42606-z

@article{9f76d03b403942849853fbf314c20c60,

title = "Author Correction: Validation of the BOADICEA model for predicting the likelihood of carrying pathogenic variants in eight breast and ovarian cancer susceptibility genes (Scientific Reports, (2023), 13, 1, (8536), 10.1038/s41598-023-35755-8)",

abstract = "Correction to: Scientific Reports, published online 26 May 2023 The original version of this Article contained an error in Results section, under {\textquoteleft}Missing information{\textquoteright} subheading, “This did not significantly alter the calibration (O/E 1.11; 95\% CI 0.97–1.26) or discrimination of the model (AUC 0.71; 95\% CI).” now reads: “This did not significantly alter the calibration (O/E 1.11; 95\% CI 0.97–1.26) or discrimination of the model (AUC 0.71; 95\% CI 0.66–0.75).” Additionally, this Article contained errors in Table 3, where the sensitivity and specificity values for BRCA1/BRCA2 at CP ≥ 3\% were incorrect. The correct and incorrect values appear below. Incorrect: (Table presented.) CP (\%) All genes BRCA1/BRCA2 Other genes Sensitivity Specificity Sensitivity Specificity Sensitivity Specificity ≥ 0 1.00 0.000 1.00 0.000 1.00 0.000 ≥ 1 1.00 0.001 1.00 0.001 1.00 0.001 ≥ 2 0.98 0.072 0.98 0.071 0.97 0.068 ≥ 3 0.92 0.19 0.87 0.36 0.87 0.18 Correct: (Table presented.) CP (\%) All genes BRCA1/BRCA2 Other genes Sensitivity Specificity Sensitivity Specificity Sensitivity Specificity ≥ 0 1.00 0.000 1.00 0.000 1.00 0.000 ≥ 1 1.00 0.001 1.00 0.001 1.00 0.001 ≥ 2 0.98 0.072 0.98 0.071 0.97 0.068 ≥ 3 0.92 0.19 0.95 0.19 0.87 0.18 The original Article has been corrected.",

author = "M{\o}ller, \{Nanna B{\ae}k\} and Boonen, \{Desir{\'e}e Sofie\} and Feldner, \{Elisabeth Simone\} and Qin Hao and Martin Larsen and L{\ae}nkholm, \{Anne Vibeke\} and {\AA}ke Borg and Anders Kvist and Therese T{\"o}rngren and Jensen, \{Uffe Birk\} and Boonen, \{Susanne Eriksen\} and Mads Thomassen and Thorkild Terkelsen",

year = "2023",

month = sep,

day = "15",

doi = "10.1038/s41598-023-42606-z",

language = "English",

volume = "13",

journal = "Scientific Reports",

issn = "2045-2322",

publisher = "Nature Publishing Group",

}

Møller, NB, Boonen, DS, Feldner, ES, Hao, Q , Larsen, M, Lænkholm, AV, Borg, Å, Kvist, A, Törngren, T, Jensen, UB, Boonen, SE , Thomassen, M & Terkelsen, T 2023, 'Author Correction: Validation of the BOADICEA model for predicting the likelihood of carrying pathogenic variants in eight breast and ovarian cancer susceptibility genes (Scientific Reports, (2023), 13, 1, (8536), 10.1038/s41598-023-35755-8)', Scientific Reports, bind 13, 15294. https://doi.org/10.1038/s41598-023-42606-z

Author Correction: Validation of the BOADICEA model for predicting the likelihood of carrying pathogenic variants in eight breast and ovarian cancer susceptibility genes (Scientific Reports, (2023), 13, 1, (8536), 10.1038/s41598-023-35755-8). / Møller, Nanna Bæk; Boonen, Desirée Sofie; Feldner, Elisabeth Simone et al.
I: Scientific Reports, Bind 13, 15294, 15.09.2023.

Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning › peer review

TY - JOUR

T1 - Author Correction

T2 - Validation of the BOADICEA model for predicting the likelihood of carrying pathogenic variants in eight breast and ovarian cancer susceptibility genes (Scientific Reports, (2023), 13, 1, (8536), 10.1038/s41598-023-35755-8)

AU - Møller, Nanna Bæk

AU - Boonen, Desirée Sofie

AU - Feldner, Elisabeth Simone

AU - Hao, Qin

AU - Larsen, Martin

AU - Lænkholm, Anne Vibeke

AU - Borg, Åke

AU - Kvist, Anders

AU - Törngren, Therese

AU - Jensen, Uffe Birk

AU - Boonen, Susanne Eriksen

AU - Thomassen, Mads

AU - Terkelsen, Thorkild

PY - 2023/9/15

Y1 - 2023/9/15

N2 - Correction to: Scientific Reports, published online 26 May 2023 The original version of this Article contained an error in Results section, under ‘Missing information’ subheading, “This did not significantly alter the calibration (O/E 1.11; 95% CI 0.97–1.26) or discrimination of the model (AUC 0.71; 95% CI).” now reads: “This did not significantly alter the calibration (O/E 1.11; 95% CI 0.97–1.26) or discrimination of the model (AUC 0.71; 95% CI 0.66–0.75).” Additionally, this Article contained errors in Table 3, where the sensitivity and specificity values for BRCA1/BRCA2 at CP ≥ 3% were incorrect. The correct and incorrect values appear below. Incorrect: (Table presented.) CP (%) All genes BRCA1/BRCA2 Other genes Sensitivity Specificity Sensitivity Specificity Sensitivity Specificity ≥ 0 1.00 0.000 1.00 0.000 1.00 0.000 ≥ 1 1.00 0.001 1.00 0.001 1.00 0.001 ≥ 2 0.98 0.072 0.98 0.071 0.97 0.068 ≥ 3 0.92 0.19 0.87 0.36 0.87 0.18 Correct: (Table presented.) CP (%) All genes BRCA1/BRCA2 Other genes Sensitivity Specificity Sensitivity Specificity Sensitivity Specificity ≥ 0 1.00 0.000 1.00 0.000 1.00 0.000 ≥ 1 1.00 0.001 1.00 0.001 1.00 0.001 ≥ 2 0.98 0.072 0.98 0.071 0.97 0.068 ≥ 3 0.92 0.19 0.95 0.19 0.87 0.18 The original Article has been corrected.

AB - Correction to: Scientific Reports, published online 26 May 2023 The original version of this Article contained an error in Results section, under ‘Missing information’ subheading, “This did not significantly alter the calibration (O/E 1.11; 95% CI 0.97–1.26) or discrimination of the model (AUC 0.71; 95% CI).” now reads: “This did not significantly alter the calibration (O/E 1.11; 95% CI 0.97–1.26) or discrimination of the model (AUC 0.71; 95% CI 0.66–0.75).” Additionally, this Article contained errors in Table 3, where the sensitivity and specificity values for BRCA1/BRCA2 at CP ≥ 3% were incorrect. The correct and incorrect values appear below. Incorrect: (Table presented.) CP (%) All genes BRCA1/BRCA2 Other genes Sensitivity Specificity Sensitivity Specificity Sensitivity Specificity ≥ 0 1.00 0.000 1.00 0.000 1.00 0.000 ≥ 1 1.00 0.001 1.00 0.001 1.00 0.001 ≥ 2 0.98 0.072 0.98 0.071 0.97 0.068 ≥ 3 0.92 0.19 0.87 0.36 0.87 0.18 Correct: (Table presented.) CP (%) All genes BRCA1/BRCA2 Other genes Sensitivity Specificity Sensitivity Specificity Sensitivity Specificity ≥ 0 1.00 0.000 1.00 0.000 1.00 0.000 ≥ 1 1.00 0.001 1.00 0.001 1.00 0.001 ≥ 2 0.98 0.072 0.98 0.071 0.97 0.068 ≥ 3 0.92 0.19 0.95 0.19 0.87 0.18 The original Article has been corrected.

U2 - 10.1038/s41598-023-42606-z

DO - 10.1038/s41598-023-42606-z

M3 - Comment/debate

C2 - 37714994

AN - SCOPUS:85171351857

SN - 2045-2322

VL - 13

JO - Scientific Reports

JF - Scientific Reports

M1 - 15294

ER -

Møller NB, Boonen DS, Feldner ES, Hao Q , Larsen M, Lænkholm AV et al. Author Correction: Validation of the BOADICEA model for predicting the likelihood of carrying pathogenic variants in eight breast and ovarian cancer susceptibility genes (Scientific Reports, (2023), 13, 1, (8536), 10.1038/s41598-023-35755-8). Scientific Reports. 2023 sep. 15;13:15294. doi: 10.1038/s41598-023-42606-z

Author Correction: Validation of the BOADICEA model for predicting the likelihood of carrying pathogenic variants in eight breast and ovarian cancer susceptibility genes (Scientific Reports, (2023), 13, 1, (8536), 10.1038/s41598-023-35755-8)

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Validation of the BOADICEA model for predicting the likelihood of carrying pathogenic variants in eight breast and ovarian cancer susceptibility genes

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