Asymmetric flow field-flow fractionation of superferrimagnetic iron oxide multicore nanoparticles

Silvio Dutz, Judith Kuntsche, Dietmar Eberbeck, Robert Müller, Matthias Zeisberger

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Magnetic nanoparticles are very useful for various medical applications where each application requires particles with specific magnetic properties. In this paper we describe the modification of the magnetic properties of magnetic multicore nanoparticles (MCNPs) by size dependent fractionation. This classification was carried out by means of asymmetric flow field-flow fractionation (AF4). A clear increase of the particle size with increasing elution time was confirmed by multi-angle laser light scattering coupled to the AF4 system, dynamic light scattering and Brownian diameters determined by magnetorelaxometry. In this way 16 fractions of particles with different hydrodynamic diameters, ranging between around 100 and 500 nm, were obtained. A high reproducibility of the method was confirmed by the comparison of the mean diameters of fractions of several fractionation runs under identical conditions. The hysteresis curves were measured by vibrating sample magnetometry. Starting from a coercivity of 1.41 kA m(-1) for the original MCNPs the coercivity of the particles in the different fractions varied from 0.41 to 3.83 kA m(-1). In our paper it is shown for the first time that fractions obtained from a broad size distributed MCNP fluid classified by AF4 show a strong correlation between hydrodynamic diameter and magnetic properties. Thus we state that AF4 is a suitable technology for reproducible size dependent classification of magnetic multicore nanoparticles suspended as ferrofluids.
OriginalsprogEngelsk
TidsskriftNanotechnology
Vol/bind23
Udgave nummer35
Sider (fra-til)355701
ISSN0957-4484
DOI
StatusUdgivet - 2012

Fingeraftryk

Fractionation
Iron oxides
Flow fields
Nanoparticles
Magnetic properties
Coercive force
Hydrodynamics
Magnetic fluids
Medical applications
Dynamic light scattering
Light scattering
Hysteresis
Particle size
ferric oxide
Fluids
Lasers

Citer dette

Dutz, Silvio ; Kuntsche, Judith ; Eberbeck, Dietmar ; Müller, Robert ; Zeisberger, Matthias. / Asymmetric flow field-flow fractionation of superferrimagnetic iron oxide multicore nanoparticles. I: Nanotechnology. 2012 ; Bind 23, Nr. 35. s. 355701.
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abstract = "Magnetic nanoparticles are very useful for various medical applications where each application requires particles with specific magnetic properties. In this paper we describe the modification of the magnetic properties of magnetic multicore nanoparticles (MCNPs) by size dependent fractionation. This classification was carried out by means of asymmetric flow field-flow fractionation (AF4). A clear increase of the particle size with increasing elution time was confirmed by multi-angle laser light scattering coupled to the AF4 system, dynamic light scattering and Brownian diameters determined by magnetorelaxometry. In this way 16 fractions of particles with different hydrodynamic diameters, ranging between around 100 and 500 nm, were obtained. A high reproducibility of the method was confirmed by the comparison of the mean diameters of fractions of several fractionation runs under identical conditions. The hysteresis curves were measured by vibrating sample magnetometry. Starting from a coercivity of 1.41 kA m(-1) for the original MCNPs the coercivity of the particles in the different fractions varied from 0.41 to 3.83 kA m(-1). In our paper it is shown for the first time that fractions obtained from a broad size distributed MCNP fluid classified by AF4 show a strong correlation between hydrodynamic diameter and magnetic properties. Thus we state that AF4 is a suitable technology for reproducible size dependent classification of magnetic multicore nanoparticles suspended as ferrofluids.",
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Asymmetric flow field-flow fractionation of superferrimagnetic iron oxide multicore nanoparticles. / Dutz, Silvio; Kuntsche, Judith; Eberbeck, Dietmar; Müller, Robert; Zeisberger, Matthias.

I: Nanotechnology, Bind 23, Nr. 35, 2012, s. 355701.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Asymmetric flow field-flow fractionation of superferrimagnetic iron oxide multicore nanoparticles

AU - Dutz, Silvio

AU - Kuntsche, Judith

AU - Eberbeck, Dietmar

AU - Müller, Robert

AU - Zeisberger, Matthias

PY - 2012

Y1 - 2012

N2 - Magnetic nanoparticles are very useful for various medical applications where each application requires particles with specific magnetic properties. In this paper we describe the modification of the magnetic properties of magnetic multicore nanoparticles (MCNPs) by size dependent fractionation. This classification was carried out by means of asymmetric flow field-flow fractionation (AF4). A clear increase of the particle size with increasing elution time was confirmed by multi-angle laser light scattering coupled to the AF4 system, dynamic light scattering and Brownian diameters determined by magnetorelaxometry. In this way 16 fractions of particles with different hydrodynamic diameters, ranging between around 100 and 500 nm, were obtained. A high reproducibility of the method was confirmed by the comparison of the mean diameters of fractions of several fractionation runs under identical conditions. The hysteresis curves were measured by vibrating sample magnetometry. Starting from a coercivity of 1.41 kA m(-1) for the original MCNPs the coercivity of the particles in the different fractions varied from 0.41 to 3.83 kA m(-1). In our paper it is shown for the first time that fractions obtained from a broad size distributed MCNP fluid classified by AF4 show a strong correlation between hydrodynamic diameter and magnetic properties. Thus we state that AF4 is a suitable technology for reproducible size dependent classification of magnetic multicore nanoparticles suspended as ferrofluids.

AB - Magnetic nanoparticles are very useful for various medical applications where each application requires particles with specific magnetic properties. In this paper we describe the modification of the magnetic properties of magnetic multicore nanoparticles (MCNPs) by size dependent fractionation. This classification was carried out by means of asymmetric flow field-flow fractionation (AF4). A clear increase of the particle size with increasing elution time was confirmed by multi-angle laser light scattering coupled to the AF4 system, dynamic light scattering and Brownian diameters determined by magnetorelaxometry. In this way 16 fractions of particles with different hydrodynamic diameters, ranging between around 100 and 500 nm, were obtained. A high reproducibility of the method was confirmed by the comparison of the mean diameters of fractions of several fractionation runs under identical conditions. The hysteresis curves were measured by vibrating sample magnetometry. Starting from a coercivity of 1.41 kA m(-1) for the original MCNPs the coercivity of the particles in the different fractions varied from 0.41 to 3.83 kA m(-1). In our paper it is shown for the first time that fractions obtained from a broad size distributed MCNP fluid classified by AF4 show a strong correlation between hydrodynamic diameter and magnetic properties. Thus we state that AF4 is a suitable technology for reproducible size dependent classification of magnetic multicore nanoparticles suspended as ferrofluids.

KW - Fractionation, Field Flow

KW - Hydrodynamics

KW - Magnetite Nanoparticles

KW - Molecular Weight

KW - Particle Size

KW - Reproducibility of Results

U2 - 10.1088/0957-4484/23/35/355701

DO - 10.1088/0957-4484/23/35/355701

M3 - Journal article

VL - 23

SP - 355701

JO - Nanotechnology

JF - Nanotechnology

SN - 0957-4484

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ER -