Aspects of posttraumatic stress disorder in long-term testicular cancer survivors: cross-sectional and longitudinal findings

A. Dahl, Maria Østby-Deglum, J. Oldenburg, R Bremnes, O. Dahl, O. Klepp, E. Wist, S. D. Fosså

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Purpose: The purpose of this research is to study the prevalence of posttraumatic stress disorder (PTSD) and variables associated with PTSD in Norwegian long-term testicular cancer survivors (TCSs) both cross-sectionally and longitudinally. Methods: At a mean of 11 years after diagnosis, 1418 TCSs responded to a mailed questionnaire, and at a mean of 19 years after diagnosis, 1046 of them responded again to a modified questionnaire. Posttraumatic symptoms related to testicular cancer were self-rated with the Impact of Event Scale (IES) at the 11-year study only. An IES total score ≥35 defined Full PTSD, and a score 26–34 identified Partial PTSD, and the combination of Full and Partial PTSD defined Probable PTSD. Results: At the 11-year study, 4.5 % had Full PTSD, 6.4 % had Partial PTSD, and 10.9 % Probable had PTSD. At both studies, socio-demographic variables, somatic health, anxiety/depression, chronic fatigue, and neurotoxic adverse effects were significantly associated with Probable PTSD in bivariate analyses. Probable anxiety disorder, poor self-rated health, and neurotoxicity remained significant with Probable PTSD in multivariate analyses at the 11-year study. In bivariate analyses, probable PTSD at that time significantly predicted socio-demographic variables, somatic health, anxiety/depression, chronic fatigue, and neurotoxicity among participants of the 19-year study, but only probable anxiety disorder remained significant in multivariable analysis. Conclusions: In spite of excellent prognosis, 10.9 % of long-term testicular cancer survivors had Probable PTSD at a mean of 11 years after diagnosis. Probable PTSD was significantly associated with a broad range of problems both at that time and was predictive of considerable problems at a mean of 19 year postdiagnosis. Implications for cancer survivors: Among long-term testicular cancer survivors, 10.9 % have Probable PTSD with many associated problems, and therefore health personnel should explore stress symptoms at follow-up since efficient treatments are available. © 2016, Springer Science+Business Media New York.
OriginalsprogEngelsk
TidsskriftJournal of Cancer Survivorship
Vol/bind10
Udgave nummer5
Sider (fra-til)842-849
ISSN1932-2259
DOI
StatusUdgivet - 2016

Citer dette

Dahl, A. ; Østby-Deglum, Maria ; Oldenburg, J. ; Bremnes, R ; Dahl, O. ; Klepp, O. ; Wist, E. ; Fosså, S. D. / Aspects of posttraumatic stress disorder in long-term testicular cancer survivors : cross-sectional and longitudinal findings. I: Journal of Cancer Survivorship. 2016 ; Bind 10, Nr. 5. s. 842-849.
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title = "Aspects of posttraumatic stress disorder in long-term testicular cancer survivors: cross-sectional and longitudinal findings",
abstract = "Purpose: The purpose of this research is to study the prevalence of posttraumatic stress disorder (PTSD) and variables associated with PTSD in Norwegian long-term testicular cancer survivors (TCSs) both cross-sectionally and longitudinally. Methods: At a mean of 11 years after diagnosis, 1418 TCSs responded to a mailed questionnaire, and at a mean of 19 years after diagnosis, 1046 of them responded again to a modified questionnaire. Posttraumatic symptoms related to testicular cancer were self-rated with the Impact of Event Scale (IES) at the 11-year study only. An IES total score ≥35 defined Full PTSD, and a score 26–34 identified Partial PTSD, and the combination of Full and Partial PTSD defined Probable PTSD. Results: At the 11-year study, 4.5 {\%} had Full PTSD, 6.4 {\%} had Partial PTSD, and 10.9 {\%} Probable had PTSD. At both studies, socio-demographic variables, somatic health, anxiety/depression, chronic fatigue, and neurotoxic adverse effects were significantly associated with Probable PTSD in bivariate analyses. Probable anxiety disorder, poor self-rated health, and neurotoxicity remained significant with Probable PTSD in multivariate analyses at the 11-year study. In bivariate analyses, probable PTSD at that time significantly predicted socio-demographic variables, somatic health, anxiety/depression, chronic fatigue, and neurotoxicity among participants of the 19-year study, but only probable anxiety disorder remained significant in multivariable analysis. Conclusions: In spite of excellent prognosis, 10.9 {\%} of long-term testicular cancer survivors had Probable PTSD at a mean of 11 years after diagnosis. Probable PTSD was significantly associated with a broad range of problems both at that time and was predictive of considerable problems at a mean of 19 year postdiagnosis. Implications for cancer survivors: Among long-term testicular cancer survivors, 10.9 {\%} have Probable PTSD with many associated problems, and therefore health personnel should explore stress symptoms at follow-up since efficient treatments are available. {\circledC} 2016, Springer Science+Business Media New York.",
author = "A. Dahl and Maria {\O}stby-Deglum and J. Oldenburg and R Bremnes and O. Dahl and O. Klepp and E. Wist and Foss{\aa}, {S. D.}",
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doi = "10.1007/s11764-016-0529-4",
language = "English",
volume = "10",
pages = "842--849",
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issn = "1932-2259",
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Dahl, A, Østby-Deglum, M, Oldenburg, J, Bremnes, R, Dahl, O, Klepp, O, Wist, E & Fosså, SD 2016, 'Aspects of posttraumatic stress disorder in long-term testicular cancer survivors: cross-sectional and longitudinal findings', Journal of Cancer Survivorship, bind 10, nr. 5, s. 842-849. https://doi.org/10.1007/s11764-016-0529-4

Aspects of posttraumatic stress disorder in long-term testicular cancer survivors : cross-sectional and longitudinal findings. / Dahl, A.; Østby-Deglum, Maria; Oldenburg, J.; Bremnes, R; Dahl, O.; Klepp, O.; Wist, E.; Fosså, S. D.

I: Journal of Cancer Survivorship, Bind 10, Nr. 5, 2016, s. 842-849.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Aspects of posttraumatic stress disorder in long-term testicular cancer survivors

T2 - cross-sectional and longitudinal findings

AU - Dahl, A.

AU - Østby-Deglum, Maria

AU - Oldenburg, J.

AU - Bremnes, R

AU - Dahl, O.

AU - Klepp, O.

AU - Wist, E.

AU - Fosså, S. D.

PY - 2016

Y1 - 2016

N2 - Purpose: The purpose of this research is to study the prevalence of posttraumatic stress disorder (PTSD) and variables associated with PTSD in Norwegian long-term testicular cancer survivors (TCSs) both cross-sectionally and longitudinally. Methods: At a mean of 11 years after diagnosis, 1418 TCSs responded to a mailed questionnaire, and at a mean of 19 years after diagnosis, 1046 of them responded again to a modified questionnaire. Posttraumatic symptoms related to testicular cancer were self-rated with the Impact of Event Scale (IES) at the 11-year study only. An IES total score ≥35 defined Full PTSD, and a score 26–34 identified Partial PTSD, and the combination of Full and Partial PTSD defined Probable PTSD. Results: At the 11-year study, 4.5 % had Full PTSD, 6.4 % had Partial PTSD, and 10.9 % Probable had PTSD. At both studies, socio-demographic variables, somatic health, anxiety/depression, chronic fatigue, and neurotoxic adverse effects were significantly associated with Probable PTSD in bivariate analyses. Probable anxiety disorder, poor self-rated health, and neurotoxicity remained significant with Probable PTSD in multivariate analyses at the 11-year study. In bivariate analyses, probable PTSD at that time significantly predicted socio-demographic variables, somatic health, anxiety/depression, chronic fatigue, and neurotoxicity among participants of the 19-year study, but only probable anxiety disorder remained significant in multivariable analysis. Conclusions: In spite of excellent prognosis, 10.9 % of long-term testicular cancer survivors had Probable PTSD at a mean of 11 years after diagnosis. Probable PTSD was significantly associated with a broad range of problems both at that time and was predictive of considerable problems at a mean of 19 year postdiagnosis. Implications for cancer survivors: Among long-term testicular cancer survivors, 10.9 % have Probable PTSD with many associated problems, and therefore health personnel should explore stress symptoms at follow-up since efficient treatments are available. © 2016, Springer Science+Business Media New York.

AB - Purpose: The purpose of this research is to study the prevalence of posttraumatic stress disorder (PTSD) and variables associated with PTSD in Norwegian long-term testicular cancer survivors (TCSs) both cross-sectionally and longitudinally. Methods: At a mean of 11 years after diagnosis, 1418 TCSs responded to a mailed questionnaire, and at a mean of 19 years after diagnosis, 1046 of them responded again to a modified questionnaire. Posttraumatic symptoms related to testicular cancer were self-rated with the Impact of Event Scale (IES) at the 11-year study only. An IES total score ≥35 defined Full PTSD, and a score 26–34 identified Partial PTSD, and the combination of Full and Partial PTSD defined Probable PTSD. Results: At the 11-year study, 4.5 % had Full PTSD, 6.4 % had Partial PTSD, and 10.9 % Probable had PTSD. At both studies, socio-demographic variables, somatic health, anxiety/depression, chronic fatigue, and neurotoxic adverse effects were significantly associated with Probable PTSD in bivariate analyses. Probable anxiety disorder, poor self-rated health, and neurotoxicity remained significant with Probable PTSD in multivariate analyses at the 11-year study. In bivariate analyses, probable PTSD at that time significantly predicted socio-demographic variables, somatic health, anxiety/depression, chronic fatigue, and neurotoxicity among participants of the 19-year study, but only probable anxiety disorder remained significant in multivariable analysis. Conclusions: In spite of excellent prognosis, 10.9 % of long-term testicular cancer survivors had Probable PTSD at a mean of 11 years after diagnosis. Probable PTSD was significantly associated with a broad range of problems both at that time and was predictive of considerable problems at a mean of 19 year postdiagnosis. Implications for cancer survivors: Among long-term testicular cancer survivors, 10.9 % have Probable PTSD with many associated problems, and therefore health personnel should explore stress symptoms at follow-up since efficient treatments are available. © 2016, Springer Science+Business Media New York.

U2 - 10.1007/s11764-016-0529-4

DO - 10.1007/s11764-016-0529-4

M3 - Journal article

C2 - 26920871

VL - 10

SP - 842

EP - 849

JO - Journal of Cancer Survivorship

JF - Journal of Cancer Survivorship

SN - 1932-2259

IS - 5

ER -