Antistoffer hos patienter med kronisk inflammatorisk demyeliniserende polyneuropati

Abdullahi Ahmed Momamed; Thomas Krøigård; Thomas Agerbo Gaist; Lars Kjøbsted Markvardsen; Søren Hein Sindrup; Henning Andersen; Morten Blaabjerg

Antistoffer hos patienter med kronisk inflammatorisk demyeliniserende polyneuropati

Abdullahi Ahmed Momamed, Thomas Krøigård, Thomas Agerbo Gaist, Lars Kjøbsted Markvardsen, Søren Hein Sindrup, Henning Andersen, Morten Blaabjerg

Aarhus Universitetshospital

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Abstract

Recent studies have identified specific immunoglobulin (Ig) G4 antibodies against the paranodal proteins neurofascin 155 and contactin 1 in subgroups of patients with chronic inflammatory demyelinating polyneuropathy (CIDP). These patients present with distinct clinical phenotypes and poor response to first-line therapy with intravenous Ig. Detection of these antibodies in patients with CIDP has diagnostic, prognostic, and therapeutic implications. This review summarises the current knowledge on clinical characteristics, pathogenesis and treatment of these patients.

Bidragets oversatte titel	Antibodies in patients with chronic inflammatory demyelinating polyneuropathy
Originalsprog	Dansk
Artikelnummer	V08180526
Tidsskrift	Ugeskrift for Læger
Vol/bind	181
Udgave nummer	16
ISSN	0041-5782
Status	Udgivet - aug. 2019

Dokumenter og links

http://ugeskriftet.dk/videnskab/antistoffer-hos-patienter-med-kronisk-inflammatorisk-demyeliniserende-polyneuropati

SDU link

Tjek adgangen til materialet i Syddansk Universitetsbiblioteks søgemaskine

Citationsformater

Momamed, A. A., Krøigård, T., Agerbo Gaist, T., Markvardsen, L. K., Sindrup, S. H., Andersen, H., & Blaabjerg, M. (2019). Antistoffer hos patienter med kronisk inflammatorisk demyeliniserende polyneuropati. Ugeskrift for Læger, 181(16), Artikel V08180526. http://ugeskriftet.dk/videnskab/antistoffer-hos-patienter-med-kronisk-inflammatorisk-demyeliniserende-polyneuropati

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title = "Antistoffer hos patienter med kronisk inflammatorisk demyeliniserende polyneuropati",

abstract = "Recent studies have identified specific immunoglobulin (Ig) G4 antibodies against the paranodal proteins neurofascin 155 and contactin 1 in subgroups of patients with chronic inflammatory demyelinating polyneuropathy (CIDP). These patients present with distinct clinical phenotypes and poor response to first-line therapy with intravenous Ig. Detection of these antibodies in patients with CIDP has diagnostic, prognostic, and therapeutic implications. This review summarises the current knowledge on clinical characteristics, pathogenesis and treatment of these patients.",

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T1 - Antistoffer hos patienter med kronisk inflammatorisk demyeliniserende polyneuropati

AU - Momamed, Abdullahi Ahmed

AU - Krøigård, Thomas

AU - Agerbo Gaist, Thomas

AU - Markvardsen, Lars Kjøbsted

AU - Sindrup, Søren Hein

AU - Andersen, Henning

AU - Blaabjerg, Morten

PY - 2019/8

Y1 - 2019/8

N2 - Recent studies have identified specific immunoglobulin (Ig) G4 antibodies against the paranodal proteins neurofascin 155 and contactin 1 in subgroups of patients with chronic inflammatory demyelinating polyneuropathy (CIDP). These patients present with distinct clinical phenotypes and poor response to first-line therapy with intravenous Ig. Detection of these antibodies in patients with CIDP has diagnostic, prognostic, and therapeutic implications. This review summarises the current knowledge on clinical characteristics, pathogenesis and treatment of these patients.

AB - Recent studies have identified specific immunoglobulin (Ig) G4 antibodies against the paranodal proteins neurofascin 155 and contactin 1 in subgroups of patients with chronic inflammatory demyelinating polyneuropathy (CIDP). These patients present with distinct clinical phenotypes and poor response to first-line therapy with intravenous Ig. Detection of these antibodies in patients with CIDP has diagnostic, prognostic, and therapeutic implications. This review summarises the current knowledge on clinical characteristics, pathogenesis and treatment of these patients.

M3 - Tidsskriftartikel

SN - 0041-5782

VL - 181

JO - Ugeskrift for Læger

JF - Ugeskrift for Læger

IS - 16

M1 - V08180526

ER -

Antistoffer hos patienter med kronisk inflammatorisk demyeliniserende polyneuropati

Abstract

Dokumenter og links

SDU link

Fingeraftryk

Citationsformater