Antisense molecules and furanose conformations - is it really that simple?

L. Kværnø, J. Wengel

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskning

    Abstrakt

    Selected nucleic acid mimics are discussed in the context of the antisense therapeutic strategy with focus on furanose conformation, RNA-binding affinity, and activation of the RNA-cleaving enzyme RNase H.

    OriginalsprogEngelsk
    TidsskriftChemical Communications
    Vol/bind2001
    Udgave nummer16
    Sider (fra-til)1419-1424
    ISSN1359-7345
    DOI
    StatusUdgivet - 2001

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