Antibiotikaresistens udgør en betydelig trussel mod bekæmpelsen af tuberkulose

Ole Skouvig Pedersen, Frauke Rudolf, Isik Somuncu Johansen, Åse Bengård Andersen, Troels Lillebæk, Christian Morberg Wejse, Victor Næstholt Dahl*

*Kontaktforfatter

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Abstract

The number of patients with drug-resistant tuberculosis (DR-TB) is increasing worldwide. This review summarises the global epidemiology of DR-TB and current treatment challenges. Luckily, novel regimens comprising bedaquiline, pretomanid, linezolid, and moxifloxacin have seemingly mitigated the global threat posed by DR-TB. However, emerging resistance against bedaquiline and pretomanid, among other factors, persists as ongoing concerns in the global fight against DR-TB. While the new regimens are groundbreaking, the sustained development of novel drugs targeting the most resistant forms of tuberculosis is of utmost importance for future efforts against DR-TB.
Bidragets oversatte titelDrug-resistant tuberculosis is a global cause of concern
OriginalsprogDansk
ArtikelnummerV11230698
TidsskriftUgeskrift for Læger
Vol/bind186
Udgave nummer14
ISSN0041-5782
DOI
StatusUdgivet - 8. jul. 2024

Emneord

  • Humans
  • Linezolid
  • Nitroimidazoles
  • Tuberculosis, Multidrug-Resistant/drug therapy

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