Abstract
The number of patients with drug-resistant tuberculosis (DR-TB) is increasing worldwide. This review summarises the global epidemiology of DR-TB and current treatment challenges. Luckily, novel regimens comprising bedaquiline, pretomanid, linezolid, and moxifloxacin have seemingly mitigated the global threat posed by DR-TB. However, emerging resistance against bedaquiline and pretomanid, among other factors, persists as ongoing concerns in the global fight against DR-TB. While the new regimens are groundbreaking, the sustained development of novel drugs targeting the most resistant forms of tuberculosis is of utmost importance for future efforts against DR-TB.
Bidragets oversatte titel | Drug-resistant tuberculosis is a global cause of concern |
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Originalsprog | Dansk |
Artikelnummer | V11230698 |
Tidsskrift | Ugeskrift for Læger |
Vol/bind | 186 |
Udgave nummer | 14 |
ISSN | 0041-5782 |
DOI | |
Status | Udgivet - 8. jul. 2024 |
Emneord
- Humans
- Linezolid
- Nitroimidazoles
- Tuberculosis, Multidrug-Resistant/drug therapy